扶正中药配合导引运动对提高肺癌患者生活质量的影响
부정중약배합도인운동대제고폐암환자생활질량적영향
Chinese herb for strengthening the body resistance and daoyin exercise in the improvement of life quality of lung cancer patients
  • 万方数据
    中国临床康复 중국림상강복
    CHINESE JOURNAL OF CLINICAL REHABILITATION
    2005年 18期 251-253 ,共3页

    刘城林%刘丽萍%张玲%苏旭春%闫冰川%孔嘉欣%金学军

    류성림%류려평%장령%소욱춘%염빙천%공가흔%금학군

    肺癌%中药%导引%生活质量 肺癌%中藥%導引%生活質量
    폐암%중약%도인%생활질량
    背景:传统中药疗法和导引运动可以改善癌症生存期患者的不适感觉,如减少疲劳感,提高对化学药物治疗的耐受性等作用已被公认.但对其效果的量化评定标准选择应该是科学的.目的:应用生活质量量表评估,扶正中药配合导引运动对肺癌患者生存状态的影响.设计:非随机化同期对照观察.单位:广州医学院临床肿瘤研究中心中西医结合科;肇庆市第一人民医院.对象:选择1997-10/2001-03广州医学院临床肿瘤研究中心中西医结合科收治的肺癌住院患者60例,男41例,女19例,其中治疗组30例,对照组30例,均为自愿参加.方法:治疗组化疗同时给以扶正中药并配合导引运动疗法,对照组给以单纯化疗.两组采用相同的化疗方案.由同一熟悉"生存质量评价表"的医师在每疗程前后评价两组患者的生活质量,同时观察两组病例化疗疗程完成情况.生活质量评价采用"中国人肺癌生存质量评价表"进行评价,内容包括肺癌引起的生理状况、社会/家庭状况、对医生及疾病态度的关系、情感状况、功能状况共5个因子.两组分别完成1,2疗程病例统计分析.主要观察指标:①两组患者治疗前后生活质量评分比较.②两组化疗疗程完成情况.结果:按意向处理分析,60例患者均完成实验.两组患者治疗前后生活质量评分比较:①治疗组治疗后生理状况评分明显低于治疗前[(14.1±3.2),(31.7±2.9)分,P＜0.01]和对照组[(20.0±3.5)分,P＜0.05].②社会/家庭状况评分明显高于治疗前[(25.2±3.1),(12.2±2.3)分,P＜0.01]也高于对照组[(19 1±2.2)分,P＜0.05].③对医生及疾病态度的关系评分明显高于治疗前[(37.4±5.2),(24.2±3.5)分,P＜0.01]也高于对照组[(29.1±3.4)分,P＜0.05].④情感状况评分明显高于治疗前(43.8±5.6),[(28.5±4.7)分,P＜0.01]也高于对照组[(34.5±3.3)分,P＜0.05].⑤功能状况评分明显高于治疗前[(26.3±2.3),(17.3±3.3)分,P＜0.01]也高于对照组[(20.3±1.1)分,P＜0.05].完成化疗情况:①治疗组完成1个疗程化疗29例[(97%),(29/30)],完成2个疗程化疗26例[(87%),(26/30)].②对照组完成1个疗程化疗26例[(87%),(26/30)],完成2个程化疗18例[(60%),(18/30)].③治疗组2个疗程化疗完成率明显高于对照组(P＜0.05).结论:扶正中药配合导引运动可以提高肺癌患者对化疗的耐受性,在一定程度上改善患者不适感觉和不适症状,从而提高其生活质量.
    배경:전통중약요법화도인운동가이개선암증생존기환자적불괄감각,여감소피로감,제고대화학약물치료적내수성등작용이피공인.단대기효과적양화평정표준선택응해시과학적.목적:응용생활질량량표평고,부정중약배합도인운동대폐암환자생존상태적영향.설계:비수궤화동기대조관찰.단위:엄주의학원림상종류연구중심중서의결합과;조경시제일인민의원.대상:선택1997-10/2001-03엄주의학원림상종류연구중심중서의결합과수치적폐암주원환자60례,남41례,녀19례,기중치료조30례,대조조30례,균위자원삼가.방법:치료조화료동시급이부정중약병배합도인운동요법,대조조급이단순화료.량조채용상동적화료방안.유동일숙실"생존질량평개표"적의사재매료정전후평개량조환자적생활질량,동시관찰량조병례화료료정완성정황.생활질량평개채용"중국인폐암생존질량평개표"진행평개,내용포괄폐암인기적생리상황、사회/가정상황、대의생급질병태도적관계、정감상황、공능상황공5개인자.량조분별완성1,2료정병례통계분석.주요관찰지표:①량조환자치료전후생활질량평분비교.②량조화료료정완성정황.결과:안의향처리분석,60례환자균완성실험.량조환자치료전후생활질량평분비교:①치료조치료후생리상황평분명현저우치료전[(14.1±3.2),(31.7±2.9)분,P＜0.01]화대조조[(20.0±3.5)분,P＜0.05].②사회/가정상황평분명현고우치료전[(25.2±3.1),(12.2±2.3)분,P＜0.01]야고우대조조[(19 1±2.2)분,P＜0.05].③대의생급질병태도적관계평분명현고우치료전[(37.4±5.2),(24.2±3.5)분,P＜0.01]야고우대조조[(29.1±3.4)분,P＜0.05].④정감상황평분명현고우치료전(43.8±5.6),[(28.5±4.7)분,P＜0.01]야고우대조조[(34.5±3.3)분,P＜0.05].⑤공능상황평분명현고우치료전[(26.3±2.3),(17.3±3.3)분,P＜0.01]야고우대조조[(20.3±1.1)분,P＜0.05].완성화료정황:①치료조완성1개료정화료29례[(97%),(29/30)],완성2개료정화료26례[(87%),(26/30)].②대조조완성1개료정화료26례[(87%),(26/30)],완성2개정화료18례[(60%),(18/30)].③치료조2개료정화료완성솔명현고우대조조(P＜0.05).결론:부정중약배합도인운동가이제고폐암환자대화료적내수성,재일정정도상개선환자불괄감각화불괄증상,종이제고기생활질량.
    BACKGROUND: It has been recognized that the traditional herbal treatment and daoyin exercises(physical and breathing exercise) can relieve the symptoms such as tiredness of cancer patients and strengthen the tolerance to chemical drugs. But the criterion of quantitative evaluation for the effect should be scientific.OBJECTIVE: To evaluate the influence of Chinese herb for strengthening the body resistance and daoyin exercises on the survival state of lung cancer patients with the evaluation scale of life quality.DESIGN: Non-randomized and concurrent controlled trial.SETTING: Department of Integrated Traditional Chinese and Western Medicine, Clinical Cancer Research Center, Guangzhou Medical College;Zhaoqing First People's Hospital.PARTICIPANTS: Totally 60 inpatients of the Department of Integrated Traditional Chinese and Western Medicine of Clinical Cancer Research Center of Guangzhou Medical College were enrolled from October 1997 to March 2001 in the study. All of them were volunteers. There were 41 males and 19 females, 30 patients in the treatment group and 30 in the control group.METHODS: The treatment group was given chemical therapy, at the same time, the herbal treatment and daoyin exercises. The control group was given chemical therapy only. The same chemical therapy was applied to both groups. The appointed doctor familiar with the evaluation table of quality of life was responsible for evaluating the quality of life of the patients in the two groups before and after treatment and the observation of their accomplishment of chemical therapy. The evaluation table of quality of life of Chinese lung cancer patients was used in the evaluation. The table included 5 factors: the physiological state caused by lung cancer, social/family state, relation of altitude towards doctor and disease, emotional state, and functional state. The statistical analysis was done to see the accomplishment of chemical therapy of two groups.chemical therapy of the two groups.RESULTS: According to the intention-to-treat analysis, 60 patients all completed the whole process of study. The comparison of the score before physiological state after treatment was obviously lower than that before treatment[ (14. 1 ± 3.2), (31.7 ±2.9) scores, P ＜ 0.01] and of control state was obviously higher than that before treatment[(25.2±3.1),(12.2 ±2.3)scores, P ＜0.01] and of control group[(19.1 ±2.2) scores,after treatment was obviously higher than that before treatment[ (37.4 ± 5.2),(24.2 ±3.5) scores, P ＜0. 01 ]and of control group[ (29. 1 ±3.4)scores, P before treatment[ (43.8 ± 5.6), (28.5 ± 4. 7) scores, P ＜ 0. 01 ] and of tional state after treatment was obviously higher than that of before treatment [(26.3±2.3), (17.3±3.3) scores, P ＜ 0.01] and of control group [ (20. 3 ± 1.1) scores, P ＜ 0. 05] . The accomplishment rate of chemical control group, 26 patients accomplished 1 course(87%, 26/30) and 18rate of 2 courses of chemical therapy of treatment group was obviously higher than that of control group ( P ＜ 0.05 ).CONCLUSION: The herbal treatment combined with daoyin exercises can improve the tolerance of lung cancer patients for chemical therapy and relieve the symptoms, thus improving their quality of life.
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