CAJ | 학술논문

目的评价X线对肺表面活性物质(PS)固尔苏治疗肺透明膜病(HMD)的疗效监测.方法回顾确诊为Ⅲ～Ⅳ级HMD、应用PS治疗的早产儿21例病例,采用用药后1/2 h、6 h、24 h、48 h、5 d胸片观察.结果用药后1/2 h胸片双肺透亮度即有改善15例;肺部表现进行性改善,较前次朐片好转16例;病变无改变或进展5例,其中并发肺出血1例,出现气漏3例;伴有肺部炎症样改变3例;动脉导管开放(PDA)11例.结论使用PS治疗后胸片动态观察能对Ⅲ～Ⅳ级HMD病变转归作出正确判断,短期复查能及时发现HMD并发症.
목적 평개X선대폐표면활성물질(PS)고이소치료폐투명막병(HMD)적료효감측.방법 회고학진위Ⅲ～Ⅳ급HMD、응용PS치료적조산인21례병례,채용용약후1/2 h、6 h、24 h、48 h、5 d흉편관찰.결과 용약후1/2 h흉편쌍폐투량도즉유개선15례;폐부표현진행성개선,교전차구편호전16례;병변무개변혹진전5례,기중병발폐출혈1례,출현기루3례;반유폐부염증양개변3례;동맥도관개방(PDA)11례.결론 사용PS치료후흉편동태관찰능대Ⅲ～Ⅳ급HMD병변전귀작출정학판단,단기복사능급시발현HMD병발증.
Objective To analyze the characteristics of the dynamic changes of the radiological X-ray images in chest after applying a pulmonary surfactant(PS) named curosurf to hyaline membrane disease in grade Ⅲ～Ⅳ of the premature lungs,and to study the clinical values of the follow-ups with chest films after applying PS to evaluate its effects and to detect the complications in chest. Methods To review the definite cases of HMD in grade Ⅲ～Ⅳ with final clinical and radiological diagnosis so as to analyze the radiological image manifestations in ehest after applying PS to the premature lungs for half an hour, for 6 hours,for 24 hours, for 48 hours and for 5 days. Results Shortly after the application of PS,according to the chest films,just half an hour later, 15 cases improved their degrees of the transmittance of the two lungs; 16 cases progressively ameliorated their manifestations in chest, taking the turn for the better than the previous images; 5 cases had no improvement, among which 1 developed a complication of pulmonary hemorrhage,and 3 developed pulmonary air leakage; 3 eases accompanied with pulmonary inflammation-like lesions; 11 cases presented patent arterial duets(PDA). Generally speaking, the X-ray image manifestation was the same as the clinical symptoms. Conclusion A dynamic observation of the X-ray films in chest after the application of PS is able to make a correct iudgement of the lesions of HMD in grade Ⅲ～Ⅳ,and can promptly detect its complications if taking a short-term review.