中国综合临床
中國綜閤臨床
중국종합림상
CLINICAL MEDICINE OF CHINA
2011年
9期
934-936
,共3页
2型糖尿病%血糖水平%脑梗死
2型糖尿病%血糖水平%腦梗死
2형당뇨병%혈당수평%뇌경사
Type 2 diabetes%Blood glucose level%Cerebral infarction
目的 分析2型糖尿病与脑梗死的相关性,以进一步指导临床工作。方法 对我院2007年1月至2010年4月收治的2型糖尿病合并脑梗死患者(糖尿病组)68例与非糖尿病脑梗死患者(非糖尿病组)76例进行对比分析,比较2组患者的血压、年龄、血清甘油三酯、总胆固醇、低密度脂蛋白胆固醇、梗死部位、梗死数目,临床特征及预后。结果 糖尿病组患者腔隙性脑梗死及多发性脑梗死发生率分别为41.2％ (28/68)及33.8％ (23/68),较非糖尿病组15.8％ (12/76)及19.8％ (15/76)明显升高,差异有统计学意义(x2 =15.5,P＜0.01);糖尿病组收缩压(155.8±24.0) mm Hg、舒张压(89.6±15.0)mm Hg、血清甘油三酯(1.6±0.3) mmol/L、低密度脂蛋白胆固醇(1.3±0.7) mmol/L,与非糖尿病组收缩压(138.5±22.0)nn Hg、舒张压(84.7±14.0) mm Hg、血清甘油三酯(1.2±0.2) mmol/L、低密度脂蛋白胆固醇(2.7 ±0.3) mmol/L比较,差异均有统计学意义(t值分别为1.96、1.65、2.03、1.85,P＜0.05或＜0.01);糖尿病组患者年龄[(50.6±6.4)岁]较非糖尿病组[(57.8±6.5)岁]明显年轻(t=1.80,P＜0.01);2组住院时间比较糖尿病组住院时间长[(17.8±5.7)d与(14.5±6.3)d,t=1.67,P＜0.05]。结论 糖尿病是脑梗死和脑梗死恶化的危险因素,早期预防或治疗糖尿病,严格控制血糖水平,同时给予控制血压、血脂等综合治疗对预防或减少缺血性梗死的发生及预后有重要的临床意义。
目的 分析2型糖尿病與腦梗死的相關性,以進一步指導臨床工作。方法 對我院2007年1月至2010年4月收治的2型糖尿病閤併腦梗死患者(糖尿病組)68例與非糖尿病腦梗死患者(非糖尿病組)76例進行對比分析,比較2組患者的血壓、年齡、血清甘油三酯、總膽固醇、低密度脂蛋白膽固醇、梗死部位、梗死數目,臨床特徵及預後。結果 糖尿病組患者腔隙性腦梗死及多髮性腦梗死髮生率分彆為41.2％ (28/68)及33.8％ (23/68),較非糖尿病組15.8％ (12/76)及19.8％ (15/76)明顯升高,差異有統計學意義(x2 =15.5,P＜0.01);糖尿病組收縮壓(155.8±24.0) mm Hg、舒張壓(89.6±15.0)mm Hg、血清甘油三酯(1.6±0.3) mmol/L、低密度脂蛋白膽固醇(1.3±0.7) mmol/L,與非糖尿病組收縮壓(138.5±22.0)nn Hg、舒張壓(84.7±14.0) mm Hg、血清甘油三酯(1.2±0.2) mmol/L、低密度脂蛋白膽固醇(2.7 ±0.3) mmol/L比較,差異均有統計學意義(t值分彆為1.96、1.65、2.03、1.85,P＜0.05或＜0.01);糖尿病組患者年齡[(50.6±6.4)歲]較非糖尿病組[(57.8±6.5)歲]明顯年輕(t=1.80,P＜0.01);2組住院時間比較糖尿病組住院時間長[(17.8±5.7)d與(14.5±6.3)d,t=1.67,P＜0.05]。結論 糖尿病是腦梗死和腦梗死噁化的危險因素,早期預防或治療糖尿病,嚴格控製血糖水平,同時給予控製血壓、血脂等綜閤治療對預防或減少缺血性梗死的髮生及預後有重要的臨床意義。
목적 분석2형당뇨병여뇌경사적상관성,이진일보지도림상공작。방법 대아원2007년1월지2010년4월수치적2형당뇨병합병뇌경사환자(당뇨병조)68례여비당뇨병뇌경사환자(비당뇨병조)76례진행대비분석,비교2조환자적혈압、년령、혈청감유삼지、총담고순、저밀도지단백담고순、경사부위、경사수목,림상특정급예후。결과 당뇨병조환자강극성뇌경사급다발성뇌경사발생솔분별위41.2％ (28/68)급33.8％ (23/68),교비당뇨병조15.8％ (12/76)급19.8％ (15/76)명현승고,차이유통계학의의(x2 =15.5,P＜0.01);당뇨병조수축압(155.8±24.0) mm Hg、서장압(89.6±15.0)mm Hg、혈청감유삼지(1.6±0.3) mmol/L、저밀도지단백담고순(1.3±0.7) mmol/L,여비당뇨병조수축압(138.5±22.0)nn Hg、서장압(84.7±14.0) mm Hg、혈청감유삼지(1.2±0.2) mmol/L、저밀도지단백담고순(2.7 ±0.3) mmol/L비교,차이균유통계학의의(t치분별위1.96、1.65、2.03、1.85,P＜0.05혹＜0.01);당뇨병조환자년령[(50.6±6.4)세]교비당뇨병조[(57.8±6.5)세]명현년경(t=1.80,P＜0.01);2조주원시간비교당뇨병조주원시간장[(17.8±5.7)d여(14.5±6.3)d,t=1.67,P＜0.05]。결론 당뇨병시뇌경사화뇌경사악화적위험인소,조기예방혹치료당뇨병,엄격공제혈당수평,동시급여공제혈압、혈지등종합치료대예방혹감소결혈성경사적발생급예후유중요적림상의의。
Objective To analyze the association between type 2 diabetics and cerebral infarction and to guide the future clinical practice.Methods A comparison study was conducted between 68 patients with Type 2 diabetes mellitus complicated with cerebral infarction(DCI) and 76 patients with cerebral infarction but no diabetic cerebral infarction (NDCI) .They were hospitalized during January 2007 and April 2010 and compared for the difference in blood pressure(BP), the cholesterol (TG), the triglyceride (TC), the lipoprotein cholesterol(LDC-C), the ages, the position of infarction, the amount of infarction, the clinical manifestations and the prognosis.Results The patients with DCI had more lacunar infarction(41.2％) and multiple infarctions (33.8％) than those with NDCI(15.8％ and 19.8％) .The difference was statistically significant (P ＜0.01) In the diabetic patients group, compared with the control group, the systolic blood pressure was ([155.8 ±24.0]mm Hg) vs.([138.5 ± 22.0]mm Hg), diastolic blood pressure was ([89.6 ± 15.0]mm Hg) vs.([84.7 ±14.0]mm Hg),the TG([1.6 ± 0.3]mmol/L vs.[1.2 ±0.2]mmol/L),the LDC-C(1.3 ±0.7]mmol/L vs.[2.7 ± 0.3]mmol/L) and the ages(50.6 ± 6.4) years vs.(57.8 ± 6.5) years.These parameters in DCI group patients were significantly higher than that of NDCI group(P ＜0.01) .The DCI patients had a longer hospitalization period ([17.8±5.7]and [14.5±6.3]d,t=1.67,P＜0.05].Conclusion Diabetes is a risk factor of cerebral infarction and of the deterioration of cerebral infarction.Prevention or treatment at a early stage of diabetes and strict control of blood sugar,the blood pressure as well as blood lipids is essential to reduce the occurrence of ischemic infarction and improve the prognosis.
