中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2011年
14期
16-17
,共2页
双硫仑样反应%抗生素%还原型谷胱甘肽
雙硫崙樣反應%抗生素%還原型穀胱甘肽
쌍류륜양반응%항생소%환원형곡광감태
Disulfiram-like reaction%Antibiotics%Reduced glutathione
目的 探讨抗生素导致双硫仑样反应的临床表现及还原型谷胱甘肽治疗双硫仑样反应的疗效.方法 分析23例双硫仑样反应患者应用抗生素与饮酒的关系及临床表现,观察还原型谷胱甘肽静脉滴注干预并辅以GICK液、补液扩容等治疗的疗效.结果 本组23例患者中15例在应用还原型谷胱甘肽后10~30 min内症状缓解,其余8例在使用GICK液辅助治疗过程中(30~180 min)恢复.结论 应用还原型谷胱甘肽治疗双硫仑样反应显效快,笔者认为有研究推广价值.
目的 探討抗生素導緻雙硫崙樣反應的臨床錶現及還原型穀胱甘肽治療雙硫崙樣反應的療效.方法 分析23例雙硫崙樣反應患者應用抗生素與飲酒的關繫及臨床錶現,觀察還原型穀胱甘肽靜脈滴註榦預併輔以GICK液、補液擴容等治療的療效.結果 本組23例患者中15例在應用還原型穀胱甘肽後10~30 min內癥狀緩解,其餘8例在使用GICK液輔助治療過程中(30~180 min)恢複.結論 應用還原型穀胱甘肽治療雙硫崙樣反應顯效快,筆者認為有研究推廣價值.
목적 탐토항생소도치쌍류륜양반응적림상표현급환원형곡광감태치료쌍류륜양반응적료효.방법 분석23례쌍류륜양반응환자응용항생소여음주적관계급림상표현,관찰환원형곡광감태정맥적주간예병보이GICK액、보액확용등치료적료효.결과 본조23례환자중15례재응용환원형곡광감태후10~30 min내증상완해,기여8례재사용GICK액보조치료과정중(30~180 min)회복.결론 응용환원형곡광감태치료쌍류륜양반응현효쾌,필자인위유연구추엄개치.
Objective To analyze the clinical manifestations of disulfiram-like reactions caused by antibiotics and investigate the therapeutical effects of reduced glutathione. Methods Twenty-three cases of disulfiram-like reaction caused by antibiotics were observed and the recovery times after administration of reduced glutathione were recorded. Results Of all 23 patients, 15 cases alleviated in 10 to 30 minutes after administration of reduced glutathione and the remained 8 cases recovered in 30 to 180 minutes after reduced glutathione treatment and GICK assistant therapy. Conclusions A better effect of reduced glutathione was observed in treating disulfiram-like reactions. This way of treating disulfiram-like reactions is recommended to further study and application by the author.
