中华全科医师杂志
中華全科醫師雜誌
중화전과의사잡지
CHINESE JOURNAL OF GENERAL PRACTITIONERS
2010年
9期
615-618
,共4页
田惠忠%武治津%张小东%杨勇
田惠忠%武治津%張小東%楊勇
전혜충%무치진%장소동%양용
下尿路症状%经尿道前列腺切除术%生活质量
下尿路癥狀%經尿道前列腺切除術%生活質量
하뇨로증상%경뇨도전렬선절제술%생활질량
Lower urinary tract symptoms%Transurethral resection of prostate%Quality of life
目的 探讨经尿道前列腺电切(TURP)对良性前列腺增生症(BPH)患者国际前列腺症状评分(IPSS)和生存质量(QOL)评分的影响.方法 对因BPH导致下尿路症状的47例男性患者(平均72岁)行TURP治疗,比较治疗前后IPSS和QOL评分以及最大尿流率、残余尿量及压力-流率检查等指标的变化,分析影响IPSS及QOL评分的因素.结果 术中均无并发症发生,术后2例前尿道狭窄,1例逆向射精,6例急迫性尿失禁加重,对症处理后症状均缓解.手术前、后IPSS及其刺激、梗阻评分分别为(22.7±4.9)与(10.5±5.8)分,(10.5±5.8)与(6.3±3.5)分,(12.1±3.9)与(4.2±3.3)分,QOL评分为(4.6±0.9)和(2.3±1.3)分,最大尿流率为(5.8±2.9)和(12.4±5.2)ml/s,残余尿量为(99±16)和(34±19)ml,差异均有统计学意义(均P＜0.01).术后随访时间、前列腺体积和急迫尿意时膀胱容量与术后IPSS有相关性(r=0.751,P＜0.05),术后随访时间和年龄与术后QOL评分有相关性(r=0.470,P＜0.05).结论 TURP对存在下尿路症状的BPH患者的IPSS、QOL评分均有显著改善,而影响IPSS和QOL评分的相关因素不尽相同.
目的 探討經尿道前列腺電切(TURP)對良性前列腺增生癥(BPH)患者國際前列腺癥狀評分(IPSS)和生存質量(QOL)評分的影響.方法 對因BPH導緻下尿路癥狀的47例男性患者(平均72歲)行TURP治療,比較治療前後IPSS和QOL評分以及最大尿流率、殘餘尿量及壓力-流率檢查等指標的變化,分析影響IPSS及QOL評分的因素.結果 術中均無併髮癥髮生,術後2例前尿道狹窄,1例逆嚮射精,6例急迫性尿失禁加重,對癥處理後癥狀均緩解.手術前、後IPSS及其刺激、梗阻評分分彆為(22.7±4.9)與(10.5±5.8)分,(10.5±5.8)與(6.3±3.5)分,(12.1±3.9)與(4.2±3.3)分,QOL評分為(4.6±0.9)和(2.3±1.3)分,最大尿流率為(5.8±2.9)和(12.4±5.2)ml/s,殘餘尿量為(99±16)和(34±19)ml,差異均有統計學意義(均P＜0.01).術後隨訪時間、前列腺體積和急迫尿意時膀胱容量與術後IPSS有相關性(r=0.751,P＜0.05),術後隨訪時間和年齡與術後QOL評分有相關性(r=0.470,P＜0.05).結論 TURP對存在下尿路癥狀的BPH患者的IPSS、QOL評分均有顯著改善,而影響IPSS和QOL評分的相關因素不儘相同.
목적 탐토경뇨도전렬선전절(TURP)대량성전렬선증생증(BPH)환자국제전렬선증상평분(IPSS)화생존질량(QOL)평분적영향.방법 대인BPH도치하뇨로증상적47례남성환자(평균72세)행TURP치료,비교치료전후IPSS화QOL평분이급최대뇨류솔、잔여뇨량급압력-류솔검사등지표적변화,분석영향IPSS급QOL평분적인소.결과 술중균무병발증발생,술후2례전뇨도협착,1례역향사정,6례급박성뇨실금가중,대증처리후증상균완해.수술전、후IPSS급기자격、경조평분분별위(22.7±4.9)여(10.5±5.8)분,(10.5±5.8)여(6.3±3.5)분,(12.1±3.9)여(4.2±3.3)분,QOL평분위(4.6±0.9)화(2.3±1.3)분,최대뇨류솔위(5.8±2.9)화(12.4±5.2)ml/s,잔여뇨량위(99±16)화(34±19)ml,차이균유통계학의의(균P＜0.01).술후수방시간、전렬선체적화급박뇨의시방광용량여술후IPSS유상관성(r=0.751,P＜0.05),술후수방시간화년령여술후QOL평분유상관성(r=0.470,P＜0.05).결론 TURP대존재하뇨로증상적BPH환자적IPSS、QOL평분균유현저개선,이영향IPSS화QOL평분적상관인소불진상동.
Objective To investigate changes in symptoms and quality of life (QOL) score before and after transurethral resection of the prostate ( TURP), and their related factors. Methods Forty-seven elderly male patients of benign prostate hyperplasia (BPH) with lower urinary tract symptoms were enrolled in the study, with an average age of 72 years. They all were undergone with TURP and evaluated with international prostate symptoms score (IPSS), QOL score, maximal urine flow rate (Qmax), residual urine volume, pressure-urine flow rate and prostate size before and after the procedure. Changes in these parameters and their related factors were analyzed. Results No complication was observed during TURP in the 47 patients. After TURP, two patients suffered from distal urethra stricture, one from retrograde ejaculation and six from aggravated urgent incontinence, and symptoms relieved with symptomatic treatment in all of them. Significant difference in overall IPSS, irritant score and obstructive score pre- and post-operation was observed P ＜ 0.01, i. e. , 22.7 ±4.9 and 10.5 ± 5.8, 10.5 ± 5.8 and 6.3 ± 3.5, and 12.1± 3.9 and 4.2 ± 3.3, respectively. QOL score was 4.6 ± 0.9 and 2.3 ± 1.3, Qmax (5.8 ± 2.9 ) ml/s and (12.4 ±5.2) ml/s and residual urine volume (99 ± 16) ml and (34 ± 19) ml pre- and post-operation,respectively ( all P ＜ 0.01 ). Follow-up time after the procedure, prostate volume and bladder volume at urgent urination desire all correlated with post-operation IPSS ( r = 0.751, P ＜ 0.05 ), and follow-up time after the procedure and age also significant correlated with post-operation QOL score (r = 0.470, P ＜ 0.05 ).Conclusions Overall IPSS, irritant score, obstructive score and QOL score improved significantly after TURP in symptomatic BPH patients, probably by varied related factors.
