中国医药
中國醫藥
중국의약
CHINA MEDICINE
2012年
9期
1107-1108
,共2页
残胃炎%胆汁反流%幽门螺杆菌感染
殘胃炎%膽汁反流%幽門螺桿菌感染
잔위염%담즙반류%유문라간균감염
Residual gastritis%Bile reflux%Helicobacter pylori infection
目的 探讨胃大部切除术后胆汁反流性残胃炎与术式、幽门螺杆菌(Hp)感染的关系及临床疗效.方法 选取我院2008年1月至2011年6月收治的胃大部切除术后胆汁反流性残胃炎患者143例作为观察组,其中采用Billroth Ⅰ术52例,采用BillrothⅡ术91例.选取同期未进行手术的患者236例作为对照组.采用快速尿素酶试验法和改良的Giemsa染色法检测患者的Hp.结果 观察组Hp感染率[24.5％(35/143)]明显低于对照组[42.8％ (101/236)](P＜0.05),Billroth Ⅰ术后患者的Hp感染率[21.2％(11/52)]略低于BillrothⅡ术后患者[26.4％ (24/91)] (P ＞0.05),Billroth Ⅰ术后患者的胆汁反流阳性率[51.9％ (27/52)]明显低于Billroth Ⅱ术后患者[80.2％ (73/91)] (P ＜0.05),胆汁反流阳性患者的Hp感染率[ 19.0％ (19/100)]明显低于胆汁反流阴性患者[37.2％ (16/43)] (P ＜0.05).结论 Hp感染是残胃炎的主要致病因素之一.胃大部切除术后胆汁反流性残胃炎患者发生Hp感染的概率大幅降低,胆汁反流是患者Hp感染的有效保护因素.
目的 探討胃大部切除術後膽汁反流性殘胃炎與術式、幽門螺桿菌(Hp)感染的關繫及臨床療效.方法 選取我院2008年1月至2011年6月收治的胃大部切除術後膽汁反流性殘胃炎患者143例作為觀察組,其中採用Billroth Ⅰ術52例,採用BillrothⅡ術91例.選取同期未進行手術的患者236例作為對照組.採用快速尿素酶試驗法和改良的Giemsa染色法檢測患者的Hp.結果 觀察組Hp感染率[24.5％(35/143)]明顯低于對照組[42.8％ (101/236)](P＜0.05),Billroth Ⅰ術後患者的Hp感染率[21.2％(11/52)]略低于BillrothⅡ術後患者[26.4％ (24/91)] (P ＞0.05),Billroth Ⅰ術後患者的膽汁反流暘性率[51.9％ (27/52)]明顯低于Billroth Ⅱ術後患者[80.2％ (73/91)] (P ＜0.05),膽汁反流暘性患者的Hp感染率[ 19.0％ (19/100)]明顯低于膽汁反流陰性患者[37.2％ (16/43)] (P ＜0.05).結論 Hp感染是殘胃炎的主要緻病因素之一.胃大部切除術後膽汁反流性殘胃炎患者髮生Hp感染的概率大幅降低,膽汁反流是患者Hp感染的有效保護因素.
목적 탐토위대부절제술후담즙반류성잔위염여술식、유문라간균(Hp)감염적관계급림상료효.방법 선취아원2008년1월지2011년6월수치적위대부절제술후담즙반류성잔위염환자143례작위관찰조,기중채용Billroth Ⅰ술52례,채용BillrothⅡ술91례.선취동기미진행수술적환자236례작위대조조.채용쾌속뇨소매시험법화개량적Giemsa염색법검측환자적Hp.결과 관찰조Hp감염솔[24.5％(35/143)]명현저우대조조[42.8％ (101/236)](P＜0.05),Billroth Ⅰ술후환자적Hp감염솔[21.2％(11/52)]략저우BillrothⅡ술후환자[26.4％ (24/91)] (P ＞0.05),Billroth Ⅰ술후환자적담즙반류양성솔[51.9％ (27/52)]명현저우Billroth Ⅱ술후환자[80.2％ (73/91)] (P ＜0.05),담즙반류양성환자적Hp감염솔[ 19.0％ (19/100)]명현저우담즙반류음성환자[37.2％ (16/43)] (P ＜0.05).결론 Hp감염시잔위염적주요치병인소지일.위대부절제술후담즙반류성잔위염환자발생Hp감염적개솔대폭강저,담즙반류시환자Hp감염적유효보호인소.
Objective To investigate the relationship among bile reflux of residual gastritis after subtotal resection,helicobacter pylori (Hp)infection and the efficacy of operation treatment.Methods One hundred and forty-three patients of subtotal resection of bile reflux of residual gastritis from January 2008 to June 2011 were selected as the observation group. Fifty-two patients received Billroth Ⅰ operation,meanwhile 91 patients received Billroth Ⅱ operation.Two hundred and thirty-six patients who did not have operations were as the control group.The rapid urease test and modified Giemsa staining method were used for the detection of patients with Helicobacter pylori.Results Hp infection rate in the observation group was lower than that in the control group [ 24.5％(35/143)vs 42.8％ (101/236),P＜0.05].Hp infection rate in Billroth Ⅰ operation patients was slightly lower than that in the Billroth Ⅱ operation patients (P ＞0.05).Bile reflux positive rate in Billroth Ⅰ operation patients was significantly lower than that in the Billroth Ⅱ operation patients [ 51.9％ (27/52 )vs 80.2％ (73/91 ),P＜0.05 ].Hp infection rate in bile reflux patients with positive was significantly lower than that in the bile reflux patients with negative [19.0％ (19/100)vs 37.2％ (16/43),P＜0.05].Conclusions Hp infection is one of the major factors causing residual gastritis.Hp infection reduces significantly in patients bile reflux gastritis after subtotal gastrectomy. Hp infection patients with bile reflux is an effective protective factor.
