CAJ | 학술논문

目的评价CO2激光与5-氨基酮戊酸光动力疗法(ALA-PDT)联合治疗尖锐湿疣的疗效及复发性.方法 124例尖锐湿疣患者随机分为两组,每组62例.治疗组采用CO2激光与ALA-PDT联合治疗,对照组单用CO2激光治疗.结果治疗组患者痊愈率为90.6%(58/62),复发率为9.4%(4/62);对照组痊愈率为76.7%(46/62),复发率为23.3%(16/62).两组在痊愈率及复发率上差异有统计学意义.结论 CO2激光联合5-氨基酮戊酸光动力疗法治疗尖锐湿疣在疗效及复发率方面均明显优于单用CO2激光治疗.
목적 평개CO2격광여5-안기동무산광동력요법(ALA-PDT)연합치료첨예습우적료효급복발성.방법 124례첨예습우환자수궤분위량조,매조62례.치료조채용CO2격광여ALA-PDT연합치료,대조조단용CO2격광치료.결과 치료조환자전유솔위90.6%(58/62),복발솔위9.4%(4/62);대조조전유솔위76.7%(46/62),복발솔위23.3%(16/62).량조재전유솔급복발솔상차이유통계학의의.결론 CO2격광연합5-안기동무산광동력요법치료첨예습우재료효급복발솔방면균명현우우단용CO2격광치료.
Objective To evaluate the effect of CO2 laser in combination with 5-aminolevulinic acidphotodynamic therapy (ALA-PDT) on clearance and recurrence of condyloma acuminatum (CA). Methods A total of 124 patients with CA were randomly and equally divided into two groups to be treated with CO2 laser plus ALA-PDT (test group) or CO2 laser only (control group). Results The cure rate and recurrence rate were 90.6% (58/62) and 9.4% (4/62), respectively in the test group, 76.7% (46/62) and 23.3% (16/62)respectively in the control group. There was a statistical difference in the cure rate and recurrence rate between he two groups (both P ＜ 0.05). Conclusion CO2 laser in combination with ALA-PDT is superior to CO2 laser alone in the treatment of CA.