CAJ | 학술논문

目的比较两种雾化吸入疗法对慢性阻塞性肺疾病(COPD)患者动脉血气分析及临床症状体征的影响.方法将90例COPD患者随机分为压缩组和氧驱组各45例,用相同剂量的硫酸沙丁胺醇雾化吸入溶液加生理盐水,分别采用压缩空气雾化吸入和氧驱雾化吸入,雾化吸入前后分别抽取动脉血行血气分析检查,同时监测患者临床症状体征的变化.结果两组患者雾化吸入前后比较,Pa02值及Sa02值均升高,两组同期比较无显著性差异(P ＞0.05);PaC02值,压缩空气吸入组降低(P＜0.05),而氧驱雾化吸入组无明显变化(P＞0.05),两组同期比较有显著性差异(P＜0.05);两组雾化吸人后临床症状体征比较,差异无显著性意义(P＞0.05).结论压缩空气雾化吸入及氧驱雾化吸入均适用于COPD患者,但对于COPD合并Ⅱ型呼吸衰竭的患者,压缩空气雾化吸入疗法优于氧驱雾化吸入.
목적 비교량충무화흡입요법대만성조새성폐질병(COPD)환자동맥혈기분석급림상증상체정적영향.방법 장90례COPD환자수궤분위압축조화양구조각45례,용상동제량적류산사정알순무화흡입용액가생리염수,분별채용압축공기무화흡입화양구무화흡입,무화흡입전후분별추취동맥혈행혈기분석검사,동시감측환자림상증상체정적변화.결과 량조환자무화흡입전후비교,Pa02치급Sa02치균승고,량조동기비교무현저성차이(P ＞0.05);PaC02치,압축공기흡입조강저(P＜0.05),이양구무화흡입조무명현변화(P＞0.05),량조동기비교유현저성차이(P＜0.05);량조무화흡인후림상증상체정비교,차이무현저성의의(P＞0.05).결론 압축공기무화흡입급양구무화흡입균괄용우COPD환자,단대우COPD합병Ⅱ형호흡쇠갈적환자,압축공기무화흡입요법우우양구무화흡입.
Objective To compare the effects of two ways of aerosol inhalation to arterial blood gas analysis and clinical symptoms and signs of patients with COPD.Methods A total of 90 patients with COPD were randomly divided into two groups,45 per group,using compressed air aerosol inhalation and oxygen aerosol inhalation separately,with the same dose of salbutamol sulfate aerosol inhalation solution and normal saline,before and after that,getting arterial blood samples to analyze blood gas,and monitoring the clinical symptoms and signs of patients at the same time.Results The PaO2 and SaO2 value of both groups of patients were increased after aerosol inhalation.There was no significant difference between the two groups ( P ＞ 0.05 ).The PaCO2 value of the compressed air group was decreased ( P ＜ 0.05 ),and had no significant change in the oxygen group ( P ＞ 0.05 ).There was significant difference between the two groups ( P ＜ 0.05 ).Clinical symptoms and signs had no significant difference between the two groups (P ＞ 0.05 ).Conclusions Compressed air aerosol inhalation and oxygen aerosol inhalation are both suitable for patients with COPD.However,for COPD patients with type - Ⅱ respiratory failure,compressed air aerosol inhalation is better than oxygen aerosol inhalation.