中华放射学杂志
中華放射學雜誌
중화방사학잡지
Chinese Journal of Radiology
2011年
5期
468-472
,共5页
张宁宁%段晓岷%段彦龙%张永红%臧晏%祁大文%孙国强%彭芸%刘宁瑶%尹光恒%曾津津
張寧寧%段曉岷%段彥龍%張永紅%臧晏%祁大文%孫國彊%彭蕓%劉寧瑤%尹光恆%曾津津
장저저%단효민%단언룡%장영홍%장안%기대문%손국강%팽예%류저요%윤광항%증진진
戈谢病%骨疾病%放射摄影术%磁共振成像
戈謝病%骨疾病%放射攝影術%磁共振成像
과사병%골질병%방사섭영술%자공진성상
Gaucher disease%Bone diseases%Radiography%Magnetic resonance imaging
目的 探讨儿童戈谢病骨骼病变的X线平片及MRI表现特点.方法 109例戈谢病患儿均行常规脊柱正、侧位及双股骨正位X线检查,同时行骨盆止位检查18例,左腕正位检查14例;14例患儿同时行股骨MR平扫.MR扫描序列为标准T1WI、T2WI、T2压脂像冠状面及矢状而扫描.综合分析其影像特点.结果 骨骼异常X线征象包括:长骨干骺端烧瓶样畸形89例(81.7%)、骨质稀疏91例(83.5%)、长骨十骺端密度不同程度的减低86例(78.9%)、骨皮质变薄69例(63.3%)、溶骨性破坏31例(28.4%)、骨硬化12例(11.0%)、骨囊性病变16例(14.7%),病理性骨折26例(23.9%),其中椎体压缩性骨折24处、股骨颈陈旧性骨折5处、脊柱弧形后凸3例、股骨头碎裂变形4例、髋关节脱位4例.,14例股骨MRI显示,T1WI及T2WI骨髓内均可见异常信号,分别表现为T1WI、T2WI信号减低4例;在T2WI及压脂像信号广泛减低的基础上出现限局性高信号或混杂信号10例.结论 儿童戈谢病骨骼病变的影像表现有一定特征性,对临床诊治及观察疗效具有较大的帮助.
目的 探討兒童戈謝病骨骼病變的X線平片及MRI錶現特點.方法 109例戈謝病患兒均行常規脊柱正、側位及雙股骨正位X線檢查,同時行骨盆止位檢查18例,左腕正位檢查14例;14例患兒同時行股骨MR平掃.MR掃描序列為標準T1WI、T2WI、T2壓脂像冠狀麵及矢狀而掃描.綜閤分析其影像特點.結果 骨骼異常X線徵象包括:長骨榦骺耑燒瓶樣畸形89例(81.7%)、骨質稀疏91例(83.5%)、長骨十骺耑密度不同程度的減低86例(78.9%)、骨皮質變薄69例(63.3%)、溶骨性破壞31例(28.4%)、骨硬化12例(11.0%)、骨囊性病變16例(14.7%),病理性骨摺26例(23.9%),其中椎體壓縮性骨摺24處、股骨頸陳舊性骨摺5處、脊柱弧形後凸3例、股骨頭碎裂變形4例、髖關節脫位4例.,14例股骨MRI顯示,T1WI及T2WI骨髓內均可見異常信號,分彆錶現為T1WI、T2WI信號減低4例;在T2WI及壓脂像信號廣汎減低的基礎上齣現限跼性高信號或混雜信號10例.結論 兒童戈謝病骨骼病變的影像錶現有一定特徵性,對臨床診治及觀察療效具有較大的幫助.
목적 탐토인동과사병골격병변적X선평편급MRI표현특점.방법 109례과사병환인균행상규척주정、측위급쌍고골정위X선검사,동시행골분지위검사18례,좌완정위검사14례;14례환인동시행고골MR평소.MR소묘서렬위표준T1WI、T2WI、T2압지상관상면급시상이소묘.종합분석기영상특점.결과 골격이상X선정상포괄:장골간후단소병양기형89례(81.7%)、골질희소91례(83.5%)、장골십후단밀도불동정도적감저86례(78.9%)、골피질변박69례(63.3%)、용골성파배31례(28.4%)、골경화12례(11.0%)、골낭성병변16례(14.7%),병이성골절26례(23.9%),기중추체압축성골절24처、고골경진구성골절5처、척주호형후철3례、고골두쇄렬변형4례、관관절탈위4례.,14례고골MRI현시,T1WI급T2WI골수내균가견이상신호,분별표현위T1WI、T2WI신호감저4례;재T2WI급압지상신호엄범감저적기출상출현한국성고신호혹혼잡신호10례.결론 인동과사병골격병변적영상표현유일정특정성,대림상진치급관찰료효구유교대적방조.
Objective To discuss the imaging features of skeletal changes in children with Gaucher disease on X-ray and MRI images.Methods One hundred and nine children with Gaucher disease were enrolled in this study.They all received routine X-ray for spine with anterior-posterior(A-P)and lateral view and bilateral femurs with A-P view.Among them.18 patients received X-ray for pelvic with A-P view.14 patients received X-ray for left wrist with A-P view.and 14 patients received MRI scan for femur.The MRI scan included T1-weighted imaging,T2-weighted imaging and fat-suppressed T2-weighted imaging with short tau inversion recovery(STIR)sequence.The imaging features of the X-ray and MRI images were analyzed retrospectively.Results The most common feature is osteoporosis,which presented in 91 cases (83.5%).Besides this,decreased density of metaphysis occurred in 86 cases(78.9%).erlenmeyer flask deformity of metaphysis occurred in 89 patients(81.7%),thinner cortex occurred in 69 cases(63.3%),osteolytic destruction occurred in 31 cases(28.4%).pathological fractures occurred in 26 cases (23.9%),osteosclerosis occurred in 12 cases(11.0%).cystic degeneration of bone occurred in 16 cases (14.7%),and dislocation of the hip occurred in 4 cases.All 14 patients received MRI presented abnormal signals.Among them,4 patients presented low signal intensity both on T1-weighted and T2-weighted images in bone marrow;the other ten presented high signal intensity mixed in low signal intensity areas on T2-weighted and fat-suppressed T2-weighted images.Conclusions The imaging features of skeletal changes in children with Gaucher disease are of some characteristics,which could provide useful information for the clinical treatment.
