中国临床实用医学
中國臨床實用醫學
중국림상실용의학
CHINA CLINICAL PRACTICAL MEDICINE
2010年
8期
110-111
,共2页
郝剑辉%郭娅慧%郝晓瑞%张渊
郝劍輝%郭婭慧%郝曉瑞%張淵
학검휘%곽아혜%학효서%장연
艾司西酞普兰%帕罗西汀%抑郁症
艾司西酞普蘭%帕囉西汀%抑鬱癥
애사서태보란%파라서정%억욱증
Escitalopram%Paroxetine%Depression
目的 观察艾司西酞普兰治疗抑郁症的疗效及安全性.方法 将68例抑郁症患者随机分为艾司西酞普兰组和帕罗西汀组,疗程6周,以汉密尔顿抑郁量表(HAMD)和汉密尔顿焦虑量表(HA-MA)评定疗效,以症状用量表(TESS)评定不良反应.结果 艾司西酞普兰组和帕罗西汀组有效率分别为94.1%和91.1%,两组疗效差异无显著性意义,但治疗1周后艾司西酞普兰组有效率高于帕罗西汀组.结论 艾司西酞普兰是一种安全有效的抗抑郁药.
目的 觀察艾司西酞普蘭治療抑鬱癥的療效及安全性.方法 將68例抑鬱癥患者隨機分為艾司西酞普蘭組和帕囉西汀組,療程6週,以漢密爾頓抑鬱量錶(HAMD)和漢密爾頓焦慮量錶(HA-MA)評定療效,以癥狀用量錶(TESS)評定不良反應.結果 艾司西酞普蘭組和帕囉西汀組有效率分彆為94.1%和91.1%,兩組療效差異無顯著性意義,但治療1週後艾司西酞普蘭組有效率高于帕囉西汀組.結論 艾司西酞普蘭是一種安全有效的抗抑鬱藥.
목적 관찰애사서태보란치료억욱증적료효급안전성.방법 장68례억욱증환자수궤분위애사서태보란조화파라서정조,료정6주,이한밀이돈억욱량표(HAMD)화한밀이돈초필량표(HA-MA)평정료효,이증상용량표(TESS)평정불량반응.결과 애사서태보란조화파라서정조유효솔분별위94.1%화91.1%,량조료효차이무현저성의의,단치료1주후애사서태보란조유효솔고우파라서정조.결론 애사서태보란시일충안전유효적항억욱약.
Objective To observe the clinical efficacy and safety of escitalporam in the treatment of depression. Methods 68 patients with depression randomly devided into escitalopram group and paroxetine group for 6 weeks. clinical efficacy was evaluated using Hamilton depression scale(HAMD) and Hamilton anxiety scale (HAMA) and treatment emergent symptoms scales(TESS)were used to evaluate the advense effects. Results The effective rate of escitalopram was94. 1% and paroxetine group was91.1%. Escitalopram group showed a highter response rate compared with paroxetine group after one week treatment. Conclusion Escitalopram is an effective and safe drug in the treatment of depression.
