CAJ | 학술논문

目的探讨重组牛碱性成纤维细胞生长因子(rbbFGF)对老年糖尿病足溃疡的疗效,总结护理方法.方法将28例老年糖尿病足溃疡患者分为治疗组和对照组各14例,对照组采用内科治疗加局部换药治疗,治疗组采用内科治疗加局部换药并外涂rbbFGF进行治疗,比较2组在肉芽组织成熟度、创面愈合时间和疗效方面的差异,并对护理方法进行总结.结果治疗组在第9、13天创面肉芽组织成熟度优于对照组；在第14、21和28天创面愈合速度优于对照组；治疗组创面愈合时间为(29.87±5.73)d,对照组为(38.49±6.58)d,2组比较差异显著；治疗4周后治疗组疗效显著优于对照组.结论 rbbFGF对老年糖尿病足溃疡具有良好的治疗效果；恰当的护理方法有助于患者的康复.
목적 탐토중조우감성성섬유세포생장인자(rbbFGF)대노년당뇨병족궤양적료효,총결호리방법.방법 장28례노년당뇨병족궤양환자분위치료조화대조조각14례,대조조채용내과치료가국부환약치료,치료조채용내과치료가국부환약병외도rbbFGF진행치료,비교2조재육아조직성숙도、창면유합시간화료효방면적차이,병대호리방법진행총결.결과 치료조재제9、13천창면육아조직성숙도우우대조조；재제14、21화28천창면유합속도우우대조조；치료조창면유합시간위(29.87±5.73)d,대조조위(38.49±6.58)d,2조비교차이현저；치료4주후치료조료효현저우우대조조.결론 rbbFGF대노년당뇨병족궤양구유량호적치료효과；흡당적호리방법유조우환자적강복.
Objective To investigate the curative effect of recombinant bovine basic fibroblast gnowth factor (rbbFGF)in the treatment of senile diabetic foot ulcer and summarize the nursing methods.Methods 28elderly patients with senile diabetic foot ulcer were divided into the control group and the treatment group with 14 patients in each group.The control group was given medical treatment and local wound dressing change,the treatment group was given rbbFGF based upon the above method.The degree of granulation tissue maturity,wound healing time and therapeutic effects were compared between these two groups.The nursing measures were summarized.Results On the 9th day and 13th day,granulation tissue maturity degree of the treatment group was better than the control group.On the 14th day,21th day and 28th day,endepidermis growth velocity of the treatment group was better than the control group.The wound healing time of the treatment group was (29.87±5.73) d and was significantly shorter than (38.49±6.58) d of thecontrol group.The therapeutic effect of the treatment group was better than that of control group on the 28th day.Conclusions Application of rbbFGF has good curative effect on senile diabetic foot ulcer and suitable nursing care methods contributes to recovery of elderly patients.