广州化工
廣州化工
엄주화공
GUANGZHOU CHEMICAL INDUSTRY AND TECHNOLOGY
2012年
3期
17-19
,共3页
喹唑啉%合成%抗肿瘤活性%研究进展
喹唑啉%閤成%抗腫瘤活性%研究進展
규서람%합성%항종류활성%연구진전
quinazoline%synthesis%antitumor activity%research advances
喹唑啉类化合物具有良好的抗肿瘤活性,主要通过对表皮生长因子受体、血管内皮细胞生长因子受体或其酪氨酸激酶的抑制作用,从而达到抗癌的功效。综述了近年来该类衍生物的合成及其抗肿瘤活性研究进展。
喹唑啉類化閤物具有良好的抗腫瘤活性,主要通過對錶皮生長因子受體、血管內皮細胞生長因子受體或其酪氨痠激酶的抑製作用,從而達到抗癌的功效。綜述瞭近年來該類衍生物的閤成及其抗腫瘤活性研究進展。
규서람류화합물구유량호적항종류활성,주요통과대표피생장인자수체、혈관내피세포생장인자수체혹기락안산격매적억제작용,종이체도항암적공효。종술료근년래해류연생물적합성급기항종류활성연구진전。
Quinazoline compounds had good antitumor activity,primarily through inhibiting the epidermal growth factor receptor,vascular endothelial growth factor receptor or its tyrosine kinase in order to play anticancer effect.Research advances in synthesis and antitumor activity were reviewed.
