湖南工业大学学报
湖南工業大學學報
호남공업대학학보
JOURNAL OF HUNAN UNIVERSITY OF TECHNOLOGY
2011年
4期
41-44
,共4页
萱草%微量元素%安全性毒理学评价
萱草%微量元素%安全性毒理學評價
훤초%미량원소%안전성독이학평개
HemerocaUisfulva%microelement%toxicological safety evaluation
为了评价萱草的食用安全性,为萱草的综合开发利用提供科学依据,对萱草中微量元素和重金属的含量进行了测量。将萱草经光波消煮后,用原子吸收分光光度计测定其矿物质和微量元素的含量,测试结果表明萱草中的矿物质和微量元素含量较丰富。并以砷为研究对象,进行了急性经口毒性、大鼠骨髓细胞微核、大鼠精子畸形、180d喂养等安全性毒理学评价试验研究。试验结果表明:所测定的45批萱草样品中,其水溶出物中的砷、汞、镉含量分别为w(砷)≤0.0618μ,g/g,w(汞)≤0.0183μg/g,w(镉)≤0.0165μg/g,均极其微小;遗传毒性试验结果无显著相关性,180d喂养试验结果显示,在本试验剂量范围内无毒副作用。研究结果表明:萱草中的微量元素含量丰富,且具有较好的食用安全性。
為瞭評價萱草的食用安全性,為萱草的綜閤開髮利用提供科學依據,對萱草中微量元素和重金屬的含量進行瞭測量。將萱草經光波消煮後,用原子吸收分光光度計測定其礦物質和微量元素的含量,測試結果錶明萱草中的礦物質和微量元素含量較豐富。併以砷為研究對象,進行瞭急性經口毒性、大鼠骨髓細胞微覈、大鼠精子畸形、180d餵養等安全性毒理學評價試驗研究。試驗結果錶明:所測定的45批萱草樣品中,其水溶齣物中的砷、汞、鎘含量分彆為w(砷)≤0.0618μ,g/g,w(汞)≤0.0183μg/g,w(鎘)≤0.0165μg/g,均極其微小;遺傳毒性試驗結果無顯著相關性,180d餵養試驗結果顯示,在本試驗劑量範圍內無毒副作用。研究結果錶明:萱草中的微量元素含量豐富,且具有較好的食用安全性。
위료평개훤초적식용안전성,위훤초적종합개발이용제공과학의거,대훤초중미량원소화중금속적함량진행료측량。장훤초경광파소자후,용원자흡수분광광도계측정기광물질화미량원소적함량,측시결과표명훤초중적광물질화미량원소함량교봉부。병이신위연구대상,진행료급성경구독성、대서골수세포미핵、대서정자기형、180d위양등안전성독이학평개시험연구。시험결과표명:소측정적45비훤초양품중,기수용출물중적신、홍、력함량분별위w(신)≤0.0618μ,g/g,w(홍)≤0.0183μg/g,w(력)≤0.0165μg/g,균겁기미소;유전독성시험결과무현저상관성,180d위양시험결과현시,재본시험제량범위내무독부작용。연구결과표명:훤초중적미량원소함량봉부,차구유교호적식용안전성。
To evaluate the food safety and provide a scientific basis for comprehensive development and utilizationof hemerocallisfulva, the contents of microelements and heavy metals in hemerocaUisfulva were measured by atomic absorption spectro-photometer after wave digestion. The results show that hemerocallisfulva is rich in minerals and trace elements. With arsenic as the research object, the toxicological safety evaluation tests were conducted, including acute oral toxicity test, rats bone marrow micronucleus test,rats sperm abnormality test and 180 d feeding test. The results show that water-soluble materials of arsenic, mercury, cadmium levels in the samples of 45 batches hemerocaUisfulva are: w (As) 〈 0.618 μg/g, w (Hg) 〈 0.183 μ/g and w (Cd)≤0.165 μg/g. The genetic toxicity test showed no significant correlation, 180 d feeding test showed that there was non-toxic and no side effects in the experimental dose range. The experiments indicate that the contents of microelements in hemerocaUisfulva are rich and it has good food safety.