西安交通大学学报(英文版)
西安交通大學學報(英文版)
서안교통대학학보(영문판)
JOURNAL OF XI'AN MEDICAL UNIVERSITY
2004年
1期
58-61
,共4页
杨团民%刘淼%杨爱玲%石宗利%邱希江%李毅%同志超%韩月
楊糰民%劉淼%楊愛玲%石宗利%邱希江%李毅%同誌超%韓月
양단민%류묘%양애령%석종리%구희강%리의%동지초%한월
DL-polylactic acid(PLA)%calcium metaphosphate(CMP)%PDLLA/CMP fiber composites%resorbable medical material%fracture healing%biocompatibility
Objective To find an ideal biomaterial for internal fixation. Methods Forty rabbits with fracture of the femur diaphysis (superiorcondyle) were treated by intramedullary nailing of femur with composites rod of resorbable DL-polylactic acid (PDLLA)-calcium metaphosphate (CMP), while steinmann's pin as control. The fracture healing, the material degradation and its mechanical properties were studied by X-ray films, macroscopic, microscopic and electron microscopic observations. Results No significant inflammatory reaction was found, and all the osteotomies were healed, while material was resorbed. Conclusion The PDLLA-CMP has excellent biocompatibility and mechanical properties, and it can be a promising implant material in orthopaedics surgery.
