CAJ | 학술논문

目的：研究观察扭伤灵搽剂的皮肤刺激性。方法：对健康家兔脱毛后多次性给予扭伤灵搽剂、赋形剂，评分标准按“中药新药临床前研究指导原则”中的相关内容，对实验结果加以评定。结果：家兔多次性涂用扭伤灵搽剂后完整皮肤刺激未见异常改变，破损皮肤涂药部位亦未出现红斑、水肿、出血点、色素沉着以及皮肤粗糙等。结论：本品在临床应用中是一种安全性较好的外用制剂。
목적：연구관찰뉴상령차제적피부자격성。방법：대건강가토탈모후다차성급여뉴상령차제、부형제，평분표준안“중약신약림상전연구지도원칙”중적상관내용，대실험결과가이평정。결과：가토다차성도용뉴상령차제후완정피부자격미견이상개변，파손피부도약부위역미출현홍반、수종、출혈점、색소침착이급피부조조등。결론：본품재림상응용중시일충안전성교호적외용제제。
Objective: To study the skin irritation of Niushang Ling liniment. Methods: To apply hair-cut healthy rabbit with Niushang Ling liniment many times, then judge the results according to “Instructive principle for preclinic study of new Chinese drug”. Results: No irritation reaction occurred in complete skin after applied Niushang Ling liniment many times and no reactions of erythema, dropsy, bleeding spots, pigmentation occurred in injured skin. Conclusion: The results indicated that the drug is effective and safe.