CAJ | 학술논문

目的探讨γ探针(γ-Probe)在前哨淋巴结探测中的地位和作用,并对中国原子能科学研究院研制的γ放免探测仪的性能进行测试和评估。方法 71例经临床证实的乳腺癌病人进行了前哨淋巴结的γ闪烁显像和γ探针定位探测。γ探针的性能重点测试定位灵敏度和空间分辨。灵敏度用点源测试,用高于本底计数10倍所对应的活度(Bq)表示。空间分辨用点源伸展函数(FSF)半高宽(FWHM)表示。γ探针在乳腺癌患者的体表测量分4个区域:前哨淋巴结区、注射区、本底区及腋窝区,用于评估γ探针在病人实际探测中的灵敏度和空间分辨。结果 γ探测仪FGDP型的灵敏度为1480Bq,空间分辨为4mmFWHM。临床应用可明显鉴别前哨淋巴结与注射区、本底区和其他部位淋巴结。结论 γ探针是一种探测前哨淋巴结的安全、简便、可靠的方法。γ放免探测仪FGDP可用于前哨淋巴结探测,其主要性能指标满足临床要求。
목적 탐토γ탐침(γ-Probe)재전초림파결탐측중적지위화작용,병대중국원자능과학연구원연제적γ방면탐측의적성능진행측시화평고。방법 71례경림상증실적유선암병인진행료전초림파결적γ섬삭현상화γ탐침정위탐측。γ탐침적성능중점측시정위령민도화공간분변。령민도용점원측시,용고우본저계수10배소대응적활도(Bq)표시。공간분변용점원신전함수(FSF)반고관(FWHM)표시。γ탐침재유선암환자적체표측량분4개구역:전초림파결구、주사구、본저구급액와구,용우평고γ탐침재병인실제탐측중적령민도화공간분변。결과 γ탐측의FGDP형적령민도위1480Bq,공간분변위4mmFWHM。림상응용가명현감별전초림파결여주사구、본저구화기타부위림파결。결론 γ탐침시일충탐측전초림파결적안전、간편、가고적방법。γ방면탐측의FGDP가용우전초림파결탐측,기주요성능지표만족림상요구。
Objective To investigate the position and usefulness of γ-probein detecting sentinel lymph node in breast cancer, and to measure and evaluate the performances of FGDP γ-probe produced by China Institute of Atomic Energy. Methods 71 clinically proved patients with breast cancer underwent γ scintigraphy and γ-probe detection. The localization sensitivity and spatial resolution of FGDP γ-probe were measured and evaluated by point source of 99mTc and point spread function (PSF) . The sensitivity was expressed by absolute activity (Bq), at the signal to background ratio of 10, and resolution-by FWHM of PST respectively. In clinical study, four areas of the patient breast were detected in order to evaluate the performances of FGDP γ-probe . Recults The sensitivity and spatial resolution of the FGDP γ-probe were 1480Bq and 4mm FWHM respectively. Counts in four areas of the patient breast can be significantly separated by FGDP γ-probe detection. Conclusions γ-probe detection is a simple,safe and accurate method for detecting sentinel lymph node in brest cancer.The performances of FGDP γ-probe are be able to meet clinical requirements for SLN detection.