CAJ | 학술논문

目的观察下呼吸道鲍曼不动杆菌感染及耐药性变化的趋势.方法回顾性调查分析2005年1月至2008年12月本院分离自住院患者痰样本的鲍曼不动杆菌及其耐药性资料.结果在4年的痰检测样本中,共分离到鲍曼不动杆菌234株,占总体痰样本细菌检出率的8.5%.所有菌株均引起下呼吸道感染,对亚胺培南、美罗培南耐药率最低,分别为4%～9%和5%～6%,对其他抗生素均有较高的耐药率.结论鲍曼不动杆菌感染以临床危重病患者(ICU、脑外科、烧伤科、呼吸内科)多见.大部分药物的鲍曼不动杆芮耐药率逐年上升.临床跃务人员应加强监测,并根据病原菌培养药敏结果选用敏感抗生素,规范抗生素应用,保持敏感抗生素的抗菌活性,以提高疗效和减缓耐药株的产生.
목적 관찰하호흡도포만불동간균감염급내약성변화적추세.방법 회고성조사분석2005년1월지2008년12월본원분리자주원환자담양본적포만불동간균급기내약성자료.결과재4년적담검측양본중,공분리도포만불동간균234주,점총체담양본세균검출솔적8.5%.소유균주균인기하호흡도감염,대아알배남、미라배남내약솔최저,분별위4%～9%화5%～6%,대기타항생소균유교고적내약솔.결론 포만불동간균감염이림상위중병환자(ICU、뇌외과、소상과、호흡내과)다견.대부분약물적포만불동간예내약솔축년상승.림상약무인원응가강감측,병근거병원균배양약민결과선용민감항생소,규범항생소응용,보지민감항생소적항균활성,이제고료효화감완내약주적산생.
Objective To investigate the infection of Acinetobacter baumannii in lower respiratory tract and the variations of trendency of drug resistance.Methods The data concerning Acinetobacter baumannii infection in our hospi-tal from January 2005 to December 2008 were retrospectively analyzed.Results Of all the sputum samples in 4 years,234 strains of Acinetobacter baumannii were isolated and the detectable rate was 8.5 %.All the strains caused lower res-piratory tract infection.The drug-resistance rate of imipenem(4%～9%)and meropenem(5%～6%)was the lowest among most of antibiotics,other antibiotics showed higher drug-resistance rate.Condusions The infections of Acineto-batter baumannii mainly happen in critical patients and most of the patients are in ICU,aural sursery departement,burns surgery department,respiratory medicine depariment.The drug-resistance rate of antibiotics shows an increasing trendency in recent years.Clinical staff should strengthen antibiotic resistance monitoring,choose antibiotics on the drug-sensitive results,standardize the drug use and improve the curative effect.