CAJ | 학술논문

目的探讨经阴道三维能量多普勒超声检测子宫内膜及内膜下血流对体外受精与胚胎移植(IVF-ET)中子宫内膜容受性的预测价值.方法应用经阴道三维能量多普勒超声,对120例接受IVFET的不孕患者,于控制性超排卵(COH)周期人绒毛膜促性腺激素(HCG)注射日进行子宫内膜厚度、内膜容积、内膜及内膜下区域的血管化指数(VI)、血流指数(FI)、血管化血流指数(VFI)测定,根据妊娠结果分为妊娠组与未妊娠组,比较两组间各参数的差异.结果 120例患者中有2例未检测到内膜血流,2例未检测到内膜下血流,1例未检测到内膜及内膜下血流,其余115例内膜和内膜下血流均显示.120例患者临床妊娠39例,妊娠率32.5%,妊娠组内膜及内膜下VI、FI、VFI均高于未妊娠组,两组间VI、FI、VFI比较差异有统计学意义(P＜0.05).内膜及内膜下VI、FI、VFI预测妊娠的ROC曲线下面积分别为0.729、0.670、0.655及0.720、0.715、0.617.结论经阴道三维能量多普勒超声检测子宫内膜及内膜下血流可以预测子宫内膜容受性,评估IVF-ET结局.
목적 탐토경음도삼유능량다보륵초성검측자궁내막급내막하혈류대체외수정여배태이식(IVF-ET)중자궁내막용수성적예측개치.방법 응용경음도삼유능량다보륵초성,대120례접수IVFET적불잉환자,우공제성초배란(COH)주기인융모막촉성선격소(HCG)주사일진행자궁내막후도、내막용적、내막급내막하구역적혈관화지수(VI)、혈류지수(FI)、혈관화혈류지수(VFI)측정,근거임신결과분위임신조여미임신조,비교량조간각삼수적차이.결과 120례환자중유2례미검측도내막혈류,2례미검측도내막하혈류,1례미검측도내막급내막하혈류,기여115례내막화내막하혈류균현시.120례환자림상임신39례,임신솔32.5%,임신조내막급내막하VI、FI、VFI균고우미임신조,량조간VI、FI、VFI비교차이유통계학의의(P＜0.05).내막급내막하VI、FI、VFI예측임신적ROC곡선하면적분별위0.729、0.670、0.655급0.720、0.715、0.617.결론 경음도삼유능량다보륵초성검측자궁내막급내막하혈류가이예측자궁내막용수성,평고IVF-ET결국.
Objective To investigate the role of endometrial and subendometrial blood flows measured by transvaginal three-dimensional(3D) power Doppler ultrasound in the prediction of endometrial receptivity during in vitro fertilization-embryo transfer (IVF-ET) cycles. Methods One hundred and twenty patients undergoing IVF-ET cycles were enrolled in this study. Transvaginal 3D power Doppler ultrasound examination was performed on the day of human chorionic gonadotropin injection to determine endometrial thickness,endometrial volume, vascularization index(VI), flow index(FI) and vascularization flow index (VFI) of endometrial and subendometrial regions by experienced sonograpbers. The patients were divided into pregnant group and non-pregnant group according to pregnant outcome. The data between the two groups were compared and analysed. Results There were no significant differences( P ＞0.05) between the pregnant group and non-pregnant group in endometrial thickness, endometrial volume. Endometrial and subendometrial VI,FI, VFI were higher in the pregnant group than those in the non-pregnant group, and statistical comparison had significant difference( P ＜0.05). Conclusions Endometrial and subendometrial blood flows measured by transvaginal 3D power Doppler ultrasound can be as a reliable indicator to assess endometrial receptivity and to predict the pregnancy outcome.