CAJ | 학술논문

目的探讨应变率显像技术定量评价成人隐匿性自身免疫性糖尿病(LADA)患者左心室长轴功能的价值.方法无合并症的LADA患者30例(LADA组),合并高血压且左心室构型正常的LADA患者30例(LADA+NLVH组);正常人30例(对照组).所有患者左室射血分数、短轴缩短率均在正常范围内且无任何心脏疾病.用应变显像分别测量长轴方向16节段心肌收缩期、舒张早期和舒张晚期的峰值应变率,分析三组之间的差异.结果 LADA组和LADA+NLVH组患者各期长轴方向16节段的峰值应变率均较正常对照组显著减低(P＜0.05或P＜0.01),LADA组与之间比较LADA+NLVH组收缩期平均峰值应变率差异无统计学意义(P＞0.05),LADA+NLVH组舒张早期和舒张晚期平均峰值应变率较LADA组明显减低(P＜0.05).结论应变率显像能够敏感、准确地评价LADA患者左心室心肌运动功能.
목적 탐토응변솔현상기술정량평개성인은닉성자신면역성당뇨병(LADA)환자좌심실장축공능적개치.방법무합병증적LADA환자30례(LADA조),합병고혈압차좌심실구형정상적LADA환자30례(LADA+NLVH조);정상인30례(대조조).소유환자좌실사혈분수、단축축단솔균재정상범위내차무임하심장질병.용응변현상분별측량장축방향16절단심기수축기、서장조기화서장만기적봉치응변솔,분석삼조지간적차이.결과 LADA조화LADA+NLVH조환자각기장축방향16절단적봉치응변솔균교정상대조조현저감저(P＜0.05혹P＜0.01),LADA조여지간비교LADA+NLVH조수축기평균봉치응변솔차이무통계학의의(P＞0.05),LADA+NLVH조서장조기화서장만기평균봉치응변솔교LADA조명현감저(P＜0.05).결론응변솔현상능구민감、준학지평개LADA환자좌심실심기운동공능.
Objective To discuss the clinical value of strain rate imaging in quantitatively evaluating segmental myocardial function of left ventricle in latent autoimmune diabetes in adult(LADA).Methods Thirty LADA without complication(LADA group),30 LADA patients with hypertension and normal geometric left ventricle(LADA+NLVH group)and 30 healthy people(control group)were enrolled.All patients had normal ejection fraction,normal fractional shortening and no cardiac symptoms.The strain rate in systolic,early and later diastolic periods were obtained from 3 consecutive heartbeats in 16 segments respectively.The parameters were quantitatively analyzed between the three groups.Results Compared with the control group,all of the measured parameter of LADA and LADA+NLVH were significantly lower(P＜0.05 or P＜0.01).Although the mean strain rate in early and later diastolic periods decreased significantly in LADA+NLVH group than in LADA group(P＜0.05),there was no significant difference in the mean systolic strain rate between the two groups (P＞0.05).Conclusions Strain rate imaging provides a sensitive and accurate tool to assess the left ventricular myocardial performance in patients with LADA.