中国组织工程研究与临床康复
中國組織工程研究與臨床康複
중국조직공정연구여림상강복
JOURNAL OF CLINICAL REHABILITATIVE TISSUE ENGINEERING RESEARCH
2011年
30期
5573-5576
,共4页
髌骨腱%生物力学%超微结构%固定%本构方程
髕骨腱%生物力學%超微結構%固定%本構方程
빈골건%생물역학%초미결구%고정%본구방정
背景:骨关节固定常作为防止受伤组织被再次损伤的方法.目的:膝关节固定对兔髌骨腱力学特性及超微形态的影响.方法:将20只成年兔等分为固定组和对照组.固定组兔左后肢通过石膏和2个可调铝夹板,保持膝伸直,踝关节屈曲90°,固定6周后,取髌骨腱-骨复合物,观察两组髌骨腱的生物力学性能和超微结构变化.结果与结论:膝关节固定6周拉伸强度和切线模量分别下降至对照组的64.44%和53.08%(P < 0.01),但两组伸长率和最大负荷差异没有显著性意义.两组材料常数及应力应变关系曲线完全不同.固定组髌骨腱的横截面积明显大于对照组(P < 0.01),小胶原纤维占有优势.说明固定不仅会导致髌骨腱生物力学的变化,而且对髌骨腱自身也产生影响.
揹景:骨關節固定常作為防止受傷組織被再次損傷的方法.目的:膝關節固定對兔髕骨腱力學特性及超微形態的影響.方法:將20隻成年兔等分為固定組和對照組.固定組兔左後肢通過石膏和2箇可調鋁夾闆,保持膝伸直,踝關節屈麯90°,固定6週後,取髕骨腱-骨複閤物,觀察兩組髕骨腱的生物力學性能和超微結構變化.結果與結論:膝關節固定6週拉伸彊度和切線模量分彆下降至對照組的64.44%和53.08%(P < 0.01),但兩組伸長率和最大負荷差異沒有顯著性意義.兩組材料常數及應力應變關繫麯線完全不同.固定組髕骨腱的橫截麵積明顯大于對照組(P < 0.01),小膠原纖維佔有優勢.說明固定不僅會導緻髕骨腱生物力學的變化,而且對髕骨腱自身也產生影響.
배경:골관절고정상작위방지수상조직피재차손상적방법.목적:슬관절고정대토빈골건역학특성급초미형태적영향.방법:장20지성년토등분위고정조화대조조.고정조토좌후지통과석고화2개가조려협판,보지슬신직,과관절굴곡90°,고정6주후,취빈골건-골복합물,관찰량조빈골건적생물역학성능화초미결구변화.결과여결론:슬관절고정6주랍신강도화절선모량분별하강지대조조적64.44%화53.08%(P < 0.01),단량조신장솔화최대부하차이몰유현저성의의.량조재료상수급응력응변관계곡선완전불동.고정조빈골건적횡절면적명현대우대조조(P < 0.01),소효원섬유점유우세.설명고정불부회도치빈골건생물역학적변화,이차대빈골건자신야산생영향.
BACKGROUND: Bone joint immobilization is often used to prevent the injured tissue from secondary injury.OBJECTIVE: To investigate the effects of knee immobilization on biomechanical changes in rabbit patellar tendon and ultrastructure morphology. METHODS: Twenty adult rabbits were assigned into two groups. The left hindlimbs of rabbits in the immobilized group (n = 10) were immobilized by plaster of paris and two adjustable aluminium splints for 6 weeks, while those left hindlimbs in the control group (n = 10) served as controls. Rabbit knees were immobilized in extension and the ankle was immobilized at 90°flexion for 6 weeks. Then the patellar tendon-bone complex was harvested to observe the biomechanical properties and ultrastructure changes of patellar tendon. RESULTS AND CONCLUSION: After 6-week immobilization, the tensile strength and tangent modulus of patellar tendon-bone complex were decreased to 64.44% and 53.08% of the control values (P < 0.01). However, there was no significant difference in the elongation at failure and the maximum load between the immobilized and control groups. The curves of stress and strain of patellar tendon based on the average material constant were greatly different. The cross-sectional area of patellar tendon was significantly larger in the immobilized group than in the control group (P < 0.01). Smaller collagen fibrils took the predominance in the immobilized group. These results showed that immobilization of knee joint could result in biomechanical changes of patellar tendon and produce influence on patellar tendon.