中华眼外伤职业眼病杂志
中華眼外傷職業眼病雜誌
중화안외상직업안병잡지
CHINESE JOURNAL OF OCULAR TRAUMA AND OCCUPATIONAL EYE DISEASE
2012年
5期
379-382
,共4页
青光眼%小梁切除术改良%丝裂霉素C
青光眼%小樑切除術改良%絲裂黴素C
청광안%소량절제술개량%사렬매소C
Glaucoma%Trabeculectomy,modified%Mitomycin C
目的 探讨改良式小梁切除术联合丝裂霉素C治疗青光眼的临床疗效.方法 应用改良式小梁切除术治疗42例64眼各型青光眼,术中一次性使用0.4 mg/ml丝裂霉素C,术后随访6～12月,观察其临床疗效及其并发症.结果 术后1个月检查,58眼(90.6％)术后视力有不同程度的提高；术后1周测眼压,所有病例眼压均有不同程度的下降,有48眼(75.0％)眼压低于21 mm Hg,术后6个月测眼压,54眼(84.4％)低于21 mmHg；末次随访时,56眼(87.5％)形成弥散扁平的功能性滤过泡,8眼(12.5％)为非功能性滤过泡；总手术成功58眼(90.6％),其中完全成功54眼(84.4％),条件成功4眼(6.3％),失败6眼(9.4％).术后主要并发症为:角膜水肿5眼,前房渗出4眼.结论 改良小梁切除术联合丝裂霉素C治疗青光眼,可有效地减少青光眼术后滤过道瘢痕的形成,充分降低眼压.该方法不需要特殊设备,手术时间短,损伤小,并发症少,手术效果好,是一种安全、有效的治疗青光眼方法.
目的 探討改良式小樑切除術聯閤絲裂黴素C治療青光眼的臨床療效.方法 應用改良式小樑切除術治療42例64眼各型青光眼,術中一次性使用0.4 mg/ml絲裂黴素C,術後隨訪6～12月,觀察其臨床療效及其併髮癥.結果 術後1箇月檢查,58眼(90.6％)術後視力有不同程度的提高；術後1週測眼壓,所有病例眼壓均有不同程度的下降,有48眼(75.0％)眼壓低于21 mm Hg,術後6箇月測眼壓,54眼(84.4％)低于21 mmHg；末次隨訪時,56眼(87.5％)形成瀰散扁平的功能性濾過泡,8眼(12.5％)為非功能性濾過泡；總手術成功58眼(90.6％),其中完全成功54眼(84.4％),條件成功4眼(6.3％),失敗6眼(9.4％).術後主要併髮癥為:角膜水腫5眼,前房滲齣4眼.結論 改良小樑切除術聯閤絲裂黴素C治療青光眼,可有效地減少青光眼術後濾過道瘢痕的形成,充分降低眼壓.該方法不需要特殊設備,手術時間短,損傷小,併髮癥少,手術效果好,是一種安全、有效的治療青光眼方法.
목적 탐토개량식소량절제술연합사렬매소C치료청광안적림상료효.방법 응용개량식소량절제술치료42례64안각형청광안,술중일차성사용0.4 mg/ml사렬매소C,술후수방6～12월,관찰기림상료효급기병발증.결과 술후1개월검사,58안(90.6％)술후시력유불동정도적제고；술후1주측안압,소유병례안압균유불동정도적하강,유48안(75.0％)안압저우21 mm Hg,술후6개월측안압,54안(84.4％)저우21 mmHg；말차수방시,56안(87.5％)형성미산편평적공능성려과포,8안(12.5％)위비공능성려과포；총수술성공58안(90.6％),기중완전성공54안(84.4％),조건성공4안(6.3％),실패6안(9.4％).술후주요병발증위:각막수종5안,전방삼출4안.결론 개량소량절제술연합사렬매소C치료청광안,가유효지감소청광안술후려과도반흔적형성,충분강저안압.해방법불수요특수설비,수술시간단,손상소,병발증소,수술효과호,시일충안전、유효적치료청광안방법.
Objective To explore the clinical efficiency of modified trabeculectomy with mitomycin C (MMC) on glaucoma.Methods 42 cases(64 eyes) with glaucoma received the modified trabeculectomy,0.4 mg/ml MMC was used in the operation.The clinical efficiency and complication were conducted.The post-operative follow-up periods ranged from 6 to 12 months.Results At 1 month,the visual acuity in 58 eyes (90.6％) increased in different le-vels,at 1 week,the IOP of all patients decreased in different levels and,48 eyes(75.0％ ) were lower than 21mmHg.At 6 months,the IOP were lower than 21 mm Hg in 54eyes (84.4％),there were diffused and flat functioning blebs in 56 eyes(87.5％ ) and non-functioning blebs in 8 eyes (12.5％).58 eyes (90.6％)had successful operations:54 eyes (84.4％) without medicine and 4 eyes( 6.3％ ) with medicine,6 eyes(9.4％ ) failed.The postoperative complications were comeal edema (5 eyes) and anterior chamber fibrin exudation(4 eyes).Conclusion Modified trabeculectomy with mitomycin C for glaucoma can effectively reduce postoperative scar adhesion of the filtration passage and lower the IOP to a target level.It is a safe and effective treatment for glaucoma,which needs no special equipments but shorter time,fewer complications and light damage.
