中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2012年
11期
1626-1627
,共2页
胃肿瘤%复发%危险因素
胃腫瘤%複髮%危險因素
위종류%복발%위험인소
Stomach neplasms%Recurrence%Risk factors
目的 探讨胃腺癌根治术后早期复发和晚期复发的影响因素.方法 回顾性分析214例胃腺癌根治术后复发患者临床资料,其中＜2年复发143例,≥2年复发71例,分析患者年龄、性别、肿瘤的部位、肿瘤的直径、肿瘤病理学分级、Borrmann分型、TNM分期、淋巴结转移、手术性质及术后有无辅助化疗等指标与胃腺癌复发的关系.结果 单因素分析显示,肿瘤直径、Borrmann分型、TNM分期、淋巴结转移、手术性质和辅助化疗与术后复发时间有关(检验值分别为8.32、16.21、24.90、5.22、17.23和3.61,均P＜0.05)；多因素分析显示,肿瘤直径和TNM分期是术后复发的独立因素(相对危险度分别为5.642和6.211,均P＜0.05).结论 肿瘤直径和TNM分期是影响胃腺癌根治术后复发的最重要的影响因素.
目的 探討胃腺癌根治術後早期複髮和晚期複髮的影響因素.方法 迴顧性分析214例胃腺癌根治術後複髮患者臨床資料,其中＜2年複髮143例,≥2年複髮71例,分析患者年齡、性彆、腫瘤的部位、腫瘤的直徑、腫瘤病理學分級、Borrmann分型、TNM分期、淋巴結轉移、手術性質及術後有無輔助化療等指標與胃腺癌複髮的關繫.結果 單因素分析顯示,腫瘤直徑、Borrmann分型、TNM分期、淋巴結轉移、手術性質和輔助化療與術後複髮時間有關(檢驗值分彆為8.32、16.21、24.90、5.22、17.23和3.61,均P＜0.05)；多因素分析顯示,腫瘤直徑和TNM分期是術後複髮的獨立因素(相對危險度分彆為5.642和6.211,均P＜0.05).結論 腫瘤直徑和TNM分期是影響胃腺癌根治術後複髮的最重要的影響因素.
목적 탐토위선암근치술후조기복발화만기복발적영향인소.방법 회고성분석214례위선암근치술후복발환자림상자료,기중＜2년복발143례,≥2년복발71례,분석환자년령、성별、종류적부위、종류적직경、종류병이학분급、Borrmann분형、TNM분기、림파결전이、수술성질급술후유무보조화료등지표여위선암복발적관계.결과 단인소분석현시,종류직경、Borrmann분형、TNM분기、림파결전이、수술성질화보조화료여술후복발시간유관(검험치분별위8.32、16.21、24.90、5.22、17.23화3.61,균P＜0.05)；다인소분석현시,종류직경화TNM분기시술후복발적독립인소(상대위험도분별위5.642화6.211,균P＜0.05).결론 종류직경화TNM분기시영향위선암근치술후복발적최중요적영향인소.
Objective To explore prognostic factors associated with early and late recurrences after surgery for patients with gastric adenocarcinoma.Methods 214 patients who underwent curative resection for gastric adenocarcinoma were divided into 2 groups according to recurrence time:an early recurrence group included 143 patients who died within 2 years after surgery,and a late reeurrence group included 71 patients who died more than 2 years after surgery.Indexes such as age,sex,tumor site,tumor size,tumor pathology classification,Borrmann type,TNM staging,lymph node metastasis,operation type and postoperative adjuvant chemotherapy were compared.Results Single factor analysis showed that the tumor diameter,Borrmann type,TNM staging,lymph node metastasis,operation type,adjuvant chemotherapy were asoceiated with postoperative recurrence( test value were 8.32,16.21,24.90,5.22,17.23 and 3.61,respectively;all P ＜ 0.05 ).Multifactor analysis showed that tumor diameter and TNM staging is recurrent independent factors( relative risk were 5.642 and 6.211,respectively ;all P ＜ 0.05 ).Conclusion Tumor size and TNM staging are the most important factors for predicting the timing of recurrence after curative resection for gastric adenocarcinoma.Clinical practice should pay attention to follow up for patients with tumor diameter≥5cm,TNM Ⅲ-Ⅳ stage,especially within two years.
