CAJ | 학술논문

目的总结胰腺导管内乳头状黏液性肿瘤(IPMN)的诊治经验,寻找术前预测浸润性IPMN的指标.方法将2003年9月-2010年7月手术治疗的27例胰腺IPMN病例分为浸润性与非浸润性IPMN两组,分析比较两组间术前资料的差异.结果浸润性IPMN 15例,非浸润性IPMN12例.两组间术前梗阻性黄疸发病率、肿瘤最大直径、血清总胆红素值有显著差异.两组间性别比例、发病年龄、是否有腹痛或腰背部疼痛、腹泻、体重减轻、新发糖尿病、血清CEA、CA19-9值差异均无统计学意义.结论血清总胆红素≥22.2μmol/L及肿瘤最大直径≥3 cm可能成为预测浸润性IPMN的指标.
목적총결이선도관내유두상점액성종류(IPMN)적진치경험,심조술전예측침윤성IPMN적지표.방법장2003년9월-2010년7월수술치료적27례이선IPMN병례분위침윤성여비침윤성IPMN량조,분석비교량조간술전자료적차이.결과침윤성IPMN 15례,비침윤성IPMN12례.량조간술전경조성황달발병솔、종류최대직경、혈청총담홍소치유현저차이.량조간성별비례、발병년령、시부유복통혹요배부동통、복사、체중감경、신발당뇨병、혈청CEA、CA19-9치차이균무통계학의의.결론혈청총담홍소≥22.2μmol/L급종류최대직경≥3 cm가능성위예측침윤성IPMN적지표.
Objective To summarize the experience in diagnosis and treatment of intraductal papillary mucinous neoplasm(IPMN) of the pancreas and identify potential preoperative factors predicting invasiveness of intraductal papillary mucinous neoplasm of the pancreas. Methods From September 2003 to July 2010,27 patients underwent pancreatic resection for IPMN. All cases were divided into invasive and noninvasive groups. Preoperative medical records were reviewed retrospectively between the two groups. Results Pathological results revealed 15 cases of invasive IPMN and 12 noninvasive cases. The incidence of obstructive jaundice, tumor size and serum total bilirubin values were significantly different between the two groups. The other factors including sex ratio, age, incidence of abdominal pain or back pain, diarrhea, weight loss, new onset diabetes, serum CEA, CA19-9 values showed no statistical difference. Conclusion Serum total bilirubin≥22.2μmol/L and tumor size≥3 cm could be predicting factors of invasive IPMN.