中国医药
中國醫藥
중국의약
CHINA MEDICINE
2012年
9期
1148-1149
,共2页
邵静宜%李建全%商广芝%李松%刘淑会
邵靜宜%李建全%商廣芝%李鬆%劉淑會
소정의%리건전%상엄지%리송%류숙회
妊娠期高血压疾病%高压氧%硝酸甘油
妊娠期高血壓疾病%高壓氧%硝痠甘油
임신기고혈압질병%고압양%초산감유
Pregnancy induced hypertension%Hyperbaric oxygen%Nitroglycerin injection
目的 通过高压氧联合硝酸甘油治疗妊娠期高血压疾病与单纯硝酸甘油治疗妊娠期高血压疾病的脐动脉血流收缩期最大血流速度/舒张期末血流速度比值(S/D比值)及阻力指数(RI)对比,探讨高压氧联合硝酸甘油在妊娠期高血压疾病治疗中的作用.方法 选择2009年5月至2011年3月妊娠期高血压疾病待产妇60例,入院时完全随机分组:单纯用硝酸甘油治疗组(对照组)和高压氧联合硝酸甘油治疗组(观察组)各30例.对照组患者给予硫酸镁,同时静脉滴注硝酸甘油.观察组在对照组治疗基础上,加用高压氧进行联合治疗.治疗前及治疗后采用彩色多普勒测脐动脉S/D比值及RI.各组患者于治疗前、后测量平均动脉压(MAP).结果 观察组胎儿脐动脉S/D比值及RI分别为2.39±0.12及0.49±0.21,对照组分别为2.50±0.11及0.58±0.25;2组比较,差异有统计学意义(P＜0.05).观察组MAP为(96±5) mm Hg,对照组MAP为(102±5) mm Hg;2组比较,差异有统计学意义(P＜0.05).结论 硝酸甘油联合高压氧治疗妊娠期高血压疾病,降压疗效确切,能改变血流变、抑制血小板聚集、降低胎儿-胎盘循环阻力,对妊娠期高血压疾病引起的胎儿宫内发育迟缓可能有治疗作用.
目的 通過高壓氧聯閤硝痠甘油治療妊娠期高血壓疾病與單純硝痠甘油治療妊娠期高血壓疾病的臍動脈血流收縮期最大血流速度/舒張期末血流速度比值(S/D比值)及阻力指數(RI)對比,探討高壓氧聯閤硝痠甘油在妊娠期高血壓疾病治療中的作用.方法 選擇2009年5月至2011年3月妊娠期高血壓疾病待產婦60例,入院時完全隨機分組:單純用硝痠甘油治療組(對照組)和高壓氧聯閤硝痠甘油治療組(觀察組)各30例.對照組患者給予硫痠鎂,同時靜脈滴註硝痠甘油.觀察組在對照組治療基礎上,加用高壓氧進行聯閤治療.治療前及治療後採用綵色多普勒測臍動脈S/D比值及RI.各組患者于治療前、後測量平均動脈壓(MAP).結果 觀察組胎兒臍動脈S/D比值及RI分彆為2.39±0.12及0.49±0.21,對照組分彆為2.50±0.11及0.58±0.25;2組比較,差異有統計學意義(P＜0.05).觀察組MAP為(96±5) mm Hg,對照組MAP為(102±5) mm Hg;2組比較,差異有統計學意義(P＜0.05).結論 硝痠甘油聯閤高壓氧治療妊娠期高血壓疾病,降壓療效確切,能改變血流變、抑製血小闆聚集、降低胎兒-胎盤循環阻力,對妊娠期高血壓疾病引起的胎兒宮內髮育遲緩可能有治療作用.
목적 통과고압양연합초산감유치료임신기고혈압질병여단순초산감유치료임신기고혈압질병적제동맥혈류수축기최대혈류속도/서장기말혈류속도비치(S/D비치)급조력지수(RI)대비,탐토고압양연합초산감유재임신기고혈압질병치료중적작용.방법 선택2009년5월지2011년3월임신기고혈압질병대산부60례,입원시완전수궤분조:단순용초산감유치료조(대조조)화고압양연합초산감유치료조(관찰조)각30례.대조조환자급여류산미,동시정맥적주초산감유.관찰조재대조조치료기출상,가용고압양진행연합치료.치료전급치료후채용채색다보륵측제동맥S/D비치급RI.각조환자우치료전、후측량평균동맥압(MAP).결과 관찰조태인제동맥S/D비치급RI분별위2.39±0.12급0.49±0.21,대조조분별위2.50±0.11급0.58±0.25;2조비교,차이유통계학의의(P＜0.05).관찰조MAP위(96±5) mm Hg,대조조MAP위(102±5) mm Hg;2조비교,차이유통계학의의(P＜0.05).결론 초산감유연합고압양치료임신기고혈압질병,강압료효학절,능개변혈류변、억제혈소판취집、강저태인-태반순배조력,대임신기고혈압질병인기적태인궁내발육지완가능유치료작용.
Objective To explore the effectiveness of hyperbaric oxygen combined with nitroglycerin in the treatment of intrauterine growth retardation. Methods Sixty cases were randomly divided into two groups:observation group and control group.The observation group was treated with hyperbaric oxygen and nitroglycerin,and the control group was given nitroglycerin only. Results The values of S/D and resistant index (RI )of umbilical arteries in observation group were 2.39±0.12,0.49±0.21,and those in control group were 2.50±0.11,0.58±0.25.There was a significant difference between two groups(P＜0.05 ).The values of mean artery pressure (MAP)in observation group was (96±5)mm Hg,and that in controlgroup was (102±5)mm Hg.The values of MAP in treatment group was more significantly reduced than that in control group after treatment.Conclusion Hyperbaric oxygen combined with nitroglycerin can obviously reduce blood pressure and significant clinical effect can be obtained by means of hyperbaric oxygen combined with nitroglycerin in the treatment of intrauterine growth retardation induced by pregnancy induced hypertension.
