中国临床实用医学
中國臨床實用醫學
중국림상실용의학
CHINA CLINICAL PRACTICAL MEDICINE
2009年
7期
19-20
,共2页
陈凤娟%漏德宝%祁慧薇%庄远非%胡辛%张羽萍%高育瑶
陳鳳娟%漏德寶%祁慧薇%莊遠非%鬍辛%張羽萍%高育瑤
진봉연%루덕보%기혜미%장원비%호신%장우평%고육요
C-反应蛋白%慢性阻塞性肺疾病%急性期%老年人
C-反應蛋白%慢性阻塞性肺疾病%急性期%老年人
C-반응단백%만성조새성폐질병%급성기%노년인
C-reactive protein%Obstructive pulmonary Diseases%Acute period%Old patients
目的 探讨血清C-反应蛋白(CRP)水平在老年COPD急性加重期的临床意义.方法 采用免疫比浊法测定入院前已用过抗生素、糖皮质激素或解热镇痛药的210例老年COPD急性加重期血清CRP水平作为临床研究对象,并以CRP,WBC,ESR和体温在感染控制前后作比较.结果 入院前用过抗生素、糖皮质激素或解热镇痛药治疗的老年COPD急性加重期患者血清CRP,WBC,ESR和体温的阳性率分别为92.38%,27.62%,48.57%,和46.67%.CRP水平与WBC,ESR和体温比较差异有显著性(P<0.01).老年COPD急性加重期感染控制前后CRP水平为58.66±15.20和8.26±1.24,比较差异有显著性(P<0.01).WBC计数在感染控制前后为8.69±2.60和5.34±1.48,比较差异有显著性(P<0.01).ESR在感染控制前后为36.81±14.23和24.52±14.61,差异有显著性(P<0.01).体温在感染控制前后为37.29±0.780e和36.26±0.370c,差异有显著性(P<0.01).结论血清CRP水平可作为老年COPD急性加重期的诊断及临床疗效评估的敏感指标,不受抗生素、糖皮质激素或解热镇痛药的影响.
目的 探討血清C-反應蛋白(CRP)水平在老年COPD急性加重期的臨床意義.方法 採用免疫比濁法測定入院前已用過抗生素、糖皮質激素或解熱鎮痛藥的210例老年COPD急性加重期血清CRP水平作為臨床研究對象,併以CRP,WBC,ESR和體溫在感染控製前後作比較.結果 入院前用過抗生素、糖皮質激素或解熱鎮痛藥治療的老年COPD急性加重期患者血清CRP,WBC,ESR和體溫的暘性率分彆為92.38%,27.62%,48.57%,和46.67%.CRP水平與WBC,ESR和體溫比較差異有顯著性(P<0.01).老年COPD急性加重期感染控製前後CRP水平為58.66±15.20和8.26±1.24,比較差異有顯著性(P<0.01).WBC計數在感染控製前後為8.69±2.60和5.34±1.48,比較差異有顯著性(P<0.01).ESR在感染控製前後為36.81±14.23和24.52±14.61,差異有顯著性(P<0.01).體溫在感染控製前後為37.29±0.780e和36.26±0.370c,差異有顯著性(P<0.01).結論血清CRP水平可作為老年COPD急性加重期的診斷及臨床療效評估的敏感指標,不受抗生素、糖皮質激素或解熱鎮痛藥的影響.
목적 탐토혈청C-반응단백(CRP)수평재노년COPD급성가중기적림상의의.방법 채용면역비탁법측정입원전이용과항생소、당피질격소혹해열진통약적210례노년COPD급성가중기혈청CRP수평작위림상연구대상,병이CRP,WBC,ESR화체온재감염공제전후작비교.결과 입원전용과항생소、당피질격소혹해열진통약치료적노년COPD급성가중기환자혈청CRP,WBC,ESR화체온적양성솔분별위92.38%,27.62%,48.57%,화46.67%.CRP수평여WBC,ESR화체온비교차이유현저성(P<0.01).노년COPD급성가중기감염공제전후CRP수평위58.66±15.20화8.26±1.24,비교차이유현저성(P<0.01).WBC계수재감염공제전후위8.69±2.60화5.34±1.48,비교차이유현저성(P<0.01).ESR재감염공제전후위36.81±14.23화24.52±14.61,차이유현저성(P<0.01).체온재감염공제전후위37.29±0.780e화36.26±0.370c,차이유현저성(P<0.01).결론혈청CRP수평가작위노년COPD급성가중기적진단급림상료효평고적민감지표,불수항생소、당피질격소혹해열진통약적영향.
Objective To explore clinical value of C-reactive protein(CRP) in acute aggressive period old patients with COPD. Methods 210 old patients in acute aggressive period with COPD were selected,who used antibiotic ,cortin or febrifuge and anodyne before. CRP,WBC,ESR and temperature were detected before and after controlling infection. Results The positive rate of CRP, WBC, ESR and temperature was 92. 38%, 27.62% ,48.57% and 46.67% respectively. The level of CRP is significant over WBC,ESR and temperature( P <0.01). The level of CRP were 58. 66±15.20 and 8.26±1.24 respectively at before and after controlling in-fection(P<0.01). The level of WBC were 8.69±2.60 and 5.34±1.48 respectively at before and after can-trolling infection(P<0.01). The level of ESR were 36.81±14.23 and 24.52±14.61 respectively at before and after controlling infection (P<0.01). The level of temperature were 37.29±0.78℃ and 36.26±0.37℃ respectively at before and after controlling infection (P<0.01). Conclusion CRP is a good marker in acute aggressive period old patients with COPD and it isn't disturbed by antibiotic,cortin or febrifuge and anodyne.
