CAJ | 학술논문

目的:动态光学乳腺成像技术(dynamic optical breast imaging, DOBI)对乳腺癌诊断指标进行初步探讨.材料和方法:接受DOBI及乳腺活检的患者共52例,均为女性.乳腺癌组19例,非乳腺癌组33例.结果:非乳腺癌感兴趣区内的"蓝色病灶"85.42%为漂移或发散,而乳腺癌68.42%为聚焦;非乳腺癌的"蓝色病灶"代谢曲线86.46%为平缓下降或呈波浪状,而乳腺癌以直线下降为多,达57.37%;64.58%非乳腺癌感兴趣区内的"蓝色病灶"代谢曲线与非蓝区代谢曲线相同,78.95%乳腺癌患者的代谢曲线与非蓝区代谢曲线不同;乳腺癌患者"蓝色病灶"代谢值(平均值为-5.77±2.13)的绝对值明显高于非乳腺癌患者(平均值为-3.34±0.87;P<0.05).结论:DOBI空间特征的局限、聚焦且稳定、代谢曲线呈陡直下降对恶性或可疑恶性病变诊断价值更大,其次为代谢值的绝对值较大(多大于|-5|).
목적:동태광학유선성상기술(dynamic optical breast imaging, DOBI)대유선암진단지표진행초보탐토.재료화방법:접수DOBI급유선활검적환자공52례,균위녀성.유선암조19례,비유선암조33례.결과:비유선암감흥취구내적"람색병조"85.42%위표이혹발산,이유선암68.42%위취초;비유선암적"람색병조"대사곡선86.46%위평완하강혹정파랑상,이유선암이직선하강위다,체57.37%;64.58%비유선암감흥취구내적"람색병조"대사곡선여비람구대사곡선상동,78.95%유선암환자적대사곡선여비람구대사곡선불동;유선암환자"람색병조"대사치(평균치위-5.77±2.13)적절대치명현고우비유선암환자(평균치위-3.34±0.87;P<0.05).결론:DOBI공간특정적국한、취초차은정、대사곡선정두직하강대악성혹가의악성병변진단개치경대,기차위대사치적절대치교대(다대우|-5|).
Purpose A new way in breast cancer detection, Dynamic Optical Breast Imaging (DOBI) was studied. Materials and Methods 52 patients receiving breast biopsy and DOBI were enrolled in this study. 19 were proved of breast cancer, 33 were benign. Results 94.8% of "blue area" in non-breast cancer lesions was found as wandering or diffusive pattern, while 68.42% breast cancer showed focal pattern. 86.46% of the curve signature of "blue area" in non-breast cancer lesions was wavy or flat, while 57.37% of breast cancer showed a steep decline. In 64.58% non-breast cancer, the curve of "blue area" was similar to that of non-blue area. 78.95% breast cancer had their curve different from that of non-blue area. The absolute value of amplitude (-5.77±2.13) of "blue area" in cancer was higher than that in non-cancer ( -3.34±0.87). The differences were all statistically significant(P<0.05). Conclusion The spatial and temporal characteristics of DOBI were of diagnostic and differential value for breast cancer. The absolute value of amplitude, over|-5|, also helped the diagnosis of breast cancer.