中华消化杂志
中華消化雜誌
중화소화잡지
Chinese Journal of Digestion
2012年
8期
509-513
,共5页
吴齐%曹长琦%李士杰%张集昌
吳齊%曹長琦%李士傑%張集昌
오제%조장기%리사걸%장집창
支架%食管肿瘤%食管狭窄%姑息疗法%吞咽障碍
支架%食管腫瘤%食管狹窄%姑息療法%吞嚥障礙
지가%식관종류%식관협착%고식요법%탄인장애
Stents%Esophageal neoplasms%Esophageal stenosis%Palliative care%Deglutition disorders
目的 探讨覆膜自膨式金属支架置入术治疗恶性食管狭窄的临床效果.方法 回顾性分析512例接受支架置入术者的临床资料,包括患者基本资料、吞咽困难缓解情况、并发症发生率及生存期.统计学处理采用t检验.结果 512例患者共置入596枚支架.支架置入前后吞咽困难分级平均值差异有统计学意义[(3.4±0.6)级比(1.1±0.8)级,t=54.09,P＜0.01].术后总体并发症发生率为14.5％(74/512),其中严重胸痛21例(4.1％)、出血16例(3.1％)、支架移位29例(5.7％)、食物嵌顿6例(1.2％)、瘘口未完全封堵2例(0.4％).获得完整随访的238例患者生存期为30～1445 d,平均218.9 d.结论 内镜下覆膜自膨式金属支架置入术可有效缓解恶性食管狭窄患者的吞咽困难症状.
目的 探討覆膜自膨式金屬支架置入術治療噁性食管狹窄的臨床效果.方法 迴顧性分析512例接受支架置入術者的臨床資料,包括患者基本資料、吞嚥睏難緩解情況、併髮癥髮生率及生存期.統計學處理採用t檢驗.結果 512例患者共置入596枚支架.支架置入前後吞嚥睏難分級平均值差異有統計學意義[(3.4±0.6)級比(1.1±0.8)級,t=54.09,P＜0.01].術後總體併髮癥髮生率為14.5％(74/512),其中嚴重胸痛21例(4.1％)、齣血16例(3.1％)、支架移位29例(5.7％)、食物嵌頓6例(1.2％)、瘺口未完全封堵2例(0.4％).穫得完整隨訪的238例患者生存期為30～1445 d,平均218.9 d.結論 內鏡下覆膜自膨式金屬支架置入術可有效緩解噁性食管狹窄患者的吞嚥睏難癥狀.
목적 탐토복막자팽식금속지가치입술치료악성식관협착적림상효과.방법 회고성분석512례접수지가치입술자적림상자료,포괄환자기본자료、탄인곤난완해정황、병발증발생솔급생존기.통계학처리채용t검험.결과 512례환자공치입596매지가.지가치입전후탄인곤난분급평균치차이유통계학의의[(3.4±0.6)급비(1.1±0.8)급,t=54.09,P＜0.01].술후총체병발증발생솔위14.5％(74/512),기중엄중흉통21례(4.1％)、출혈16례(3.1％)、지가이위29례(5.7％)、식물감돈6례(1.2％)、루구미완전봉도2례(0.4％).획득완정수방적238례환자생존기위30～1445 d,평균218.9 d.결론 내경하복막자팽식금속지가치입술가유효완해악성식관협착환자적탄인곤난증상.
Objective To investigate the clinical efficacy of covered self-expanding metal stent in the treatment of malignant esophageal stricture.Methods The clinical data of 512 patients accepted stent were retrospectively analyzed,which included patients' profiles,relief of dysphagia,incidence of complications and survival period.The data were analyzed by t test.Results A total of 596 stents were placed in 512 patients.There was significant difference in mean dysphagia score between before and after stent placement (grade 3.4±0.6 vs grade 1.1±0.8,t=54.09,P＜0.01).After the placement,the overall incidence of complications was 14.5％ (74/512),of which there were 21 cases of severe retrosternal pain (4.1％),16 cases of bleeding (3.1 ％),29 cases of stent displacement (5.7％),six cases of food impaction (1.2％),two cases of fistula without completely blocked (0.4％).The survival period of 238 patients with complete follow-up ranged from 30 to 1445 days,the mean time was 218.9 days.Conclusion Endoscopic covered self-expanding metal stent placement may effectively relieve dysphagia symptoms in patients with malignant esophageal stricture.
