中华医学美学美容杂志
中華醫學美學美容雜誌
중화의학미학미용잡지
CHINESE JOURNAL OF MEDICAL AESTHETICS AND COSMETOLOGY
2011年
5期
344-347
,共4页
光动力疗法%鲜红斑痣%光敏剂
光動力療法%鮮紅斑痣%光敏劑
광동력요법%선홍반지%광민제
Photodynamic therapy%Port-wine stain%Photosensitizer
目的 探讨光动力疗法(photodynamic therapy,PDT)治疗鲜红斑痣的临床疗效和安全性.方法 采用PDT治疗鲜红斑痣125例.根据患者体重,静脉推注相应的光敏剂PSD-007后,皮损局部行铜蒸气激光照射,至红斑肿胀渗出为治疗结点;每次治疗前采集红斑图像以评价治疗效果.2个月后复诊,采用5级分类法评价前次治疗的效果,并进行患者满意度调查,根据红斑减退变平等情况决定治疗结束或继续下一个疗程治疗.结果 PDT治疗鲜红斑痣临床效果明显,治疗后即可出现明显的畸形血管肿胀封闭,经过4个疗程的治疗,治愈率达49.60％,显效率达96.00％,其中经过不到2个疗程的治疗,治愈率即达到13.60％.在整个治疗过程中,患者满意率为95.20％.结论 PDT治疗鲜红斑痣疗效显著,美容效果好,不良反应小,值得临床推广应用.
目的 探討光動力療法(photodynamic therapy,PDT)治療鮮紅斑痣的臨床療效和安全性.方法 採用PDT治療鮮紅斑痣125例.根據患者體重,靜脈推註相應的光敏劑PSD-007後,皮損跼部行銅蒸氣激光照射,至紅斑腫脹滲齣為治療結點;每次治療前採集紅斑圖像以評價治療效果.2箇月後複診,採用5級分類法評價前次治療的效果,併進行患者滿意度調查,根據紅斑減退變平等情況決定治療結束或繼續下一箇療程治療.結果 PDT治療鮮紅斑痣臨床效果明顯,治療後即可齣現明顯的畸形血管腫脹封閉,經過4箇療程的治療,治愈率達49.60％,顯效率達96.00％,其中經過不到2箇療程的治療,治愈率即達到13.60％.在整箇治療過程中,患者滿意率為95.20％.結論 PDT治療鮮紅斑痣療效顯著,美容效果好,不良反應小,值得臨床推廣應用.
목적 탐토광동력요법(photodynamic therapy,PDT)치료선홍반지적림상료효화안전성.방법 채용PDT치료선홍반지125례.근거환자체중,정맥추주상응적광민제PSD-007후,피손국부행동증기격광조사,지홍반종창삼출위치료결점;매차치료전채집홍반도상이평개치료효과.2개월후복진,채용5급분류법평개전차치료적효과,병진행환자만의도조사,근거홍반감퇴변평등정황결정치료결속혹계속하일개료정치료.결과 PDT치료선홍반지림상효과명현,치료후즉가출현명현적기형혈관종창봉폐,경과4개료정적치료,치유솔체49.60％,현효솔체96.00％,기중경과불도2개료정적치료,치유솔즉체도13.60％.재정개치료과정중,환자만의솔위95.20％.결론 PDT치료선홍반지료효현저,미용효과호,불량반응소,치득림상추엄응용.
Objective To observe the improvement in manifestation of port wine stains (PWS) with photodynamic therapy (PDT),and to further evaluate the safety and efficacy of PDT in treatment of PWS.Methods A total of 125 patients with PWS were treated with PDT.The lesion of PWS was exposured to the copper vapor laser locally after injection of photosensitizer PSD-007 based on the weight of body via vein.Before each session,lesions were photographed,and therapeutic effects were evaluated by physicians based on improvement in color,thickness,and lesion area recorded on the photos.Return visit was carried out after 2 months.The improvement rate was classified as 5 grades to value the therapeutic effect of last treatment.In addition,patients satisfaction was also investigated.The treatment was determined to terminate or continue depending on the change of red spot including color fading and flatting.Results Patients with PWS responsed remarkably to the PDT.The healing rate was 49.60 ％ and excellence rate 96.00 ％ after less than 4 session treatments.Among the total of healing patients,13.60 ％00 were released from PWS with no more than 2 courses of treat ment.The satisfactory rate of patients was 95.20 ％ during observation.Conclusions PDT is a safe and highly effective treatment for PWS with good cosmetic results in the dermatologic clinic.
