CAJ | 학술논문

目的论述微量元素对细胞外基质代谢的影响，探讨创伤愈合的生理和相关病理机制。方法以基础研究结合相关临床资料，分析微量元素与细胞外基质代谢的关系，探讨创伤修复机制。结果在创伤愈合过程中，微量元素通过参与酶的构成与激活、构成体内重要的载体及蛋白质成份、参与激素和维生素的合成以及调控自由基水平等功能，广泛参与到胶原蛋白和其它细胞外基质的合成、分解、沉积与重建过程中。结论微量元素对细胞外基质的代谢起着一定的调控作用，在创伤愈合过程中发挥着重要作用。
목적논술미량원소대세포외기질대사적영향，탐토창상유합적생리화상관병리궤제。방법이기출연구결합상관림상자료，분석미량원소여세포외기질대사적관계，탐토창상수복궤제。결과재창상유합과정중，미량원소통과삼여매적구성여격활、구성체내중요적재체급단백질성빈、삼여격소화유생소적합성이급조공자유기수평등공능，엄범삼여도효원단백화기타세포외기질적합성、분해、침적여중건과정중。결론미량원소대세포외기질적대사기착일정적조공작용，재창상유합과정중발휘착중요작용。
Objective　To investigate the effects of trace elements on the metabolism of extracellular matrix and explore the physiological and pathological mechanism of trauma. Methods　Based on the experimental and clinical data, it was studied that the action of trace elements in the metabolism of extracellular matrix in trauma repairing. Results　During wound healing, the trace elements were the components of many kinds of enzymes, carriers and proteins. They took part in the synthesis of hormones and vitamins as well as the transmission of information system. They activated many different kinds of enzymes and regulate the levels of free radicals. The trace elements had the complicated effects on the synthesis, decompose, deposition and reconstruction of collagen and other extracellular matrix. Conclusion　The trace elements play an important role in regulating the metabolism of extracellular matrix.