中华行为医学与脑科学杂志
中華行為醫學與腦科學雜誌
중화행위의학여뇌과학잡지
CHINESE JOURNAL OF BEHAVIORAL MEDICINE AND BRAIN SCIENCE
2011年
11期
999-1001
,共3页
闭眼%睁眼%默认模式网络%事件相关电位,P300,区域能量%区域电位
閉眼%睜眼%默認模式網絡%事件相關電位,P300,區域能量%區域電位
폐안%정안%묵인모식망락%사건상관전위,P300,구역능량%구역전위
Eyes-closed,Eyes-open,EEG DMN%ERPs,P300,Field power%Field potential
目的 探讨静息闭眼及睁眼脑电图(EEG)脑能量对听觉诱发电位P300的影响.方法 招募12名健康男性在校大学生(20～24岁),分别在其闭眼及睁眼时先记录2minEEG,然后进行听觉P300实验.结果 ①Alpha波主要分布在顶枕区,Alpha-1 (7.5～ 9.5 Hz)区域能量[闭眼(2.62±0.81)μV2,睁眼(1.81±0.56) μV2],差异有显著性(P＜0.01)；Alpha-2( 10～12 Hz)区域能量[闭眼(8.55±1.85) μV2,睁眼(4.95±1.59) μV2],差异有显著性(P＜0.05).②P300实验标准刺激诱发电位以N1(90ms)及P2(180 ms)成分为主,闭眼和睁眼差异无显著性；新异刺激诱发电位以N2(207 ms)及P3(313 ms)成分为主,N2区域电位闭眼[(0.01±0.71)μV]较睁眼[(-2.13±0.80)μV]减小,差异显著(P＜0.01)；P3区域电位闭眼[ (4.16±1.08) μV]较睁眼[(4.78±1.20)μV]减小,差异无显著性.结论 静息闭眼状态Alpha区域能量明显高于睁眼,而在听觉诱发电位P300范式N2区域负向电位明显小于睁眼状态.
目的 探討靜息閉眼及睜眼腦電圖(EEG)腦能量對聽覺誘髮電位P300的影響.方法 招募12名健康男性在校大學生(20～24歲),分彆在其閉眼及睜眼時先記錄2minEEG,然後進行聽覺P300實驗.結果 ①Alpha波主要分佈在頂枕區,Alpha-1 (7.5～ 9.5 Hz)區域能量[閉眼(2.62±0.81)μV2,睜眼(1.81±0.56) μV2],差異有顯著性(P＜0.01)；Alpha-2( 10～12 Hz)區域能量[閉眼(8.55±1.85) μV2,睜眼(4.95±1.59) μV2],差異有顯著性(P＜0.05).②P300實驗標準刺激誘髮電位以N1(90ms)及P2(180 ms)成分為主,閉眼和睜眼差異無顯著性；新異刺激誘髮電位以N2(207 ms)及P3(313 ms)成分為主,N2區域電位閉眼[(0.01±0.71)μV]較睜眼[(-2.13±0.80)μV]減小,差異顯著(P＜0.01)；P3區域電位閉眼[ (4.16±1.08) μV]較睜眼[(4.78±1.20)μV]減小,差異無顯著性.結論 靜息閉眼狀態Alpha區域能量明顯高于睜眼,而在聽覺誘髮電位P300範式N2區域負嚮電位明顯小于睜眼狀態.
목적 탐토정식폐안급정안뇌전도(EEG)뇌능량대은각유발전위P300적영향.방법 초모12명건강남성재교대학생(20～24세),분별재기폐안급정안시선기록2minEEG,연후진행은각P300실험.결과 ①Alpha파주요분포재정침구,Alpha-1 (7.5～ 9.5 Hz)구역능량[폐안(2.62±0.81)μV2,정안(1.81±0.56) μV2],차이유현저성(P＜0.01)；Alpha-2( 10～12 Hz)구역능량[폐안(8.55±1.85) μV2,정안(4.95±1.59) μV2],차이유현저성(P＜0.05).②P300실험표준자격유발전위이N1(90ms)급P2(180 ms)성분위주,폐안화정안차이무현저성；신이자격유발전위이N2(207 ms)급P3(313 ms)성분위주,N2구역전위폐안[(0.01±0.71)μV]교정안[(-2.13±0.80)μV]감소,차이현저(P＜0.01)；P3구역전위폐안[ (4.16±1.08) μV]교정안[(4.78±1.20)μV]감소,차이무현저성.결론 정식폐안상태Alpha구역능량명현고우정안,이재은각유발전위P300범식N2구역부향전위명현소우정안상태.
Objective To investigate the effects of eyes-closed (EC) and eyes-open (EO) EEG field powers on the auditory P300 evoke potentials.Methods The EEG was recorded in 12 healthy male college students (20 ～24 years) respectively in their eyes-closed and eyes-open states,and then the auditory P300 paradigm was performed.Results ① Alpha band was distributed at the posterior-occipital area,while Alpha-1 (7.5～9.5 Hz) field power were EC as (2.62 ±0.81 ) μV2 and EO as ( 1.80 ±0.56) μV2,with statistical significance (P ＜ 0.01 ) ; Alpha-2 ( 10 ～ 12 Hz) field power were EC as ( 8.55 ± 1.85 ) μV2 and EO as (4.95 ± 1.59 )μV2,also with statistical significance (P＜0.05).②In P300,the Common stimulus elicited clear component N1 (90ms)and P2 (180ms) in the ERPs after stimulus,while there were no significant differences between EC and EO states.Correspondingly,the rare stimulus elicited clear component N2 (207 ms) and P3 (313 ms) in the ERPs after stimulus on-set.Comparing the differences of field potentials of the rare stimulus between the two states,N2field potential in EC ( (0.01 ± 0.71 ) μV) was smaller than that in EO ( ( - 2.13 ± 0.80 ) μV ),with statistical significance (P ＜ 0.05 ) ; while P3 field potential in the EC ( ( 4.16 ± 1.08 ) μV ) was smaller than that in EO ( (4.78 ± 1.20) μV),but without statistical significance (P ＞ 0.05 ).Conclusion The alpha field power is higher in eyes-closed than in eyes-open state,while performing the same auditory P300 paradigm,significant reduction of field potential in the N2 component are observed in eyes-closed than in eyes-open state.
