CAJ | 학술논문

目的探讨壶腹周围癌术后局部复发的治疗方法.方法回顾分析1997年1月至2007年5月23例壶腹周围癌术后复发病例的治疗,其中3例行再手术切除,5例剖腹探查术中行射频消融,10例行高强度聚焦超声热疗,5例行区域性动脉灌注化疗.结果本组壶腹周围癌术后局部复发再手术切除率为13%.2例术后生存期分别为10个月和13个月,另1例术后至今6个月仍无瘤生存.20例通过射频消融、高强度聚焦超声热疗及区域性动脉灌注化疗后症状均有不同程度地缓解.结论对于壶腹周围癌术后局部复发患者,再次手术切除有助于减轻症状,延长生存期;对不能手术者,可选择射频消融、高强度聚焦超声热疗和区域性动脉灌注化疗治疗.
목적 탐토호복주위암술후국부복발적치료방법.방법 회고분석1997년1월지2007년5월23례호복주위암술후복발병례적치료,기중3례행재수술절제,5례부복탐사술중행사빈소융,10례행고강도취초초성열료,5례행구역성동맥관주화료.결과 본조호복주위암술후국부복발재수술절제솔위13%.2례술후생존기분별위10개월화13개월,령1례술후지금6개월잉무류생존.20례통과사빈소융、고강도취초초성열료급구역성동맥관주화료후증상균유불동정도지완해.결론 대우호복주위암술후국부복발환자,재차수술절제유조우감경증상,연장생존기;대불능수술자,가선택사빈소융、고강도취초초성열료화구역성동맥관주화료치료.
Objective To evaluate the treatment modalities for local recurrent periampullary carcinoma. Methods From January 1997 to May 2007, 23 patients with local recurrent periampullary carcinoma underwent different therapy. The recurrent tumor was resected through laparotomy in 3 cases and the unresectable tumors were treated with radiofrequency ablation(RFA) in 5 patients. In 10 patients and 5 patients respectively high intensity focused ultrasound ( HIFU ) and regional chemotherapy ( RC ) were performed. Results The resection rate for local recurrent periampullary carcinoma was 13% in this group, 2 patients have survived for 10 months and 13 months respectively after reoperation while one patient achieved tumor-free survival for six months so far. The symptoms were alleviated to some extent in 20 patients treated with RFA, HIFU or RC. Conclusions Resection of local recurrent periampullary carcinoma may benefit a longer survival time, and the improvement of the quality of life. RFA, HIFU and RC are the alternative modalities for patients with unresectable tumors.