CAJ | 학술논문

目的观察急性心肌梗死(AMI)住院患者肾功能对AMI患者预后的影响。方法调查680例AMI住院患者的肾功能状况，有肾功能损伤的228例患者作为观察组，其余作为对照组。分析两组患者的临床特点、院内病死率，并观察两组患者1年病死率及1年内心力衰竭、心绞痛以及再次心肌梗死的发生情况。结果与对照组相比，观察组患者年龄大，女性多，多具有高血压、糖尿病、冠心病等病史，院内(17.08％与9.74％)及1年病死率（25.00％与14.44％）高，心血管事件发生率（57.14％与38.96％）高。结论 AMI伴有肾功能损伤患者合并症多，病情重，预后差。肾功能损伤是影响AMI患者预后的独立危险因素。
목적 관찰급성심기경사(AMI)주원환자신공능대AMI환자예후적영향。방법 조사680례AMI주원환자적신공능상황，유신공능손상적228례환자작위관찰조，기여작위대조조。분석량조환자적림상특점、원내병사솔，병관찰량조환자1년병사솔급1년내심력쇠갈、심교통이급재차심기경사적발생정황。결과 여대조조상비，관찰조환자년령대，녀성다，다구유고혈압、당뇨병、관심병등병사，원내(17.08％여9.74％)급1년병사솔（25.00％여14.44％）고，심혈관사건발생솔（57.14％여38.96％）고。결론 AMI반유신공능손상환자합병증다，병정중，예후차。신공능손상시영향AMI환자예후적독립위험인소。
Objective To investigate the renal function of the patients with acute myocardial infarction (AMI) and its effect on patients' outcome.Methods The renal function of 680 patients with AMI,received the conventional therapies, such as thrmbolysis, antiplatelet and antianginal therapies were investigated. According to it, 228 patients with renal dysfunction[GFR ＜90ml · min-1 · ( 1.73m2 ) -1]were divided into observation group,while the others[GFR≥90ml · min-1 · (1.73m2) -1]were divided into control group. To analyse their clinical characteristics、the inhospital mortality、one year mortality and the heart ocurrence rate in one year. Results Compared with the patients in the control group,the patients in the observation group were older、more likely to be women、and more likely to have hypertension、diabetes mellitus、coronary heart disease. The inhospital and one year mortality were higher ( 17. 8％ vs 9.74％ ,P ＜0. 01 ;25.00％ vs 14. 44％ ,P ＜0. 01 ) and the heart ocurrence rate was higher(57. 14％ vs38. 96％ ,P ＜ 0. 01 ) in one year in the observation group than that in the control group. ConclosionThe AMI patients with renal dysfunction were more likely to have concomitant diseases, worse ill condition and outcome. Renal dysfunction was an independent risk factor for the outcome in the patients with AMI.