CAJ | 학술논문

目的分析山东省地方性氟中毒的病情现状,为制订防治策略提供科学依据.方法 2008年按照国家<2007年地方病防治项目技术实施方案>的要求,选择山东省19个县(市、区)以村为单位进行流行病学调查,氟离子选择电极法测定水氟和8～12岁儿童尿氟,Dean法诊断儿童氟斑牙,临床和X线摄片检查16岁以上成人氟骨症.结果在19个县(市、区)中,共调查了186个村,水氟均值≤1.00 mg/L的村44个,占23.66%(44/186);＞1.00 mg/L的村142个,占76.34%(142/186);水氟最大值为8.88 mg/L.8～12岁儿童氟斑牙总检出率为66.35%(4518/6809),氟斑牙指数为1.55,缺损率为15.39%(1048/6809).儿童尿氟＞1.40mg/L的人数占83.29%(2149/2580),最高值为31.92 mg/L.16岁以上成人氟骨症临床和X线检出率分别为6.37%(5577/87 607)、20.23%(229/1132).结论山东省地方性氟中毒病情仍然比较严重,防治形势依然比较严峻,须进一步加大防治力度.
목적 분석산동성지방성불중독적병정현상,위제정방치책략제공과학의거.방법 2008년안조국가<2007년지방병방치항목기술실시방안>적요구,선택산동성19개현(시、구)이촌위단위진행류행병학조사,불리자선택전겁법측정수불화8～12세인동뇨불,Dean법진단인동불반아,림상화X선섭편검사16세이상성인불골증.결과 재19개현(시、구)중,공조사료186개촌,수불균치≤1.00 mg/L적촌44개,점23.66%(44/186);＞1.00 mg/L적촌142개,점76.34%(142/186);수불최대치위8.88 mg/L.8～12세인동불반아총검출솔위66.35%(4518/6809),불반아지수위1.55,결손솔위15.39%(1048/6809).인동뇨불＞1.40mg/L적인수점83.29%(2149/2580),최고치위31.92 mg/L.16세이상성인불골증림상화X선검출솔분별위6.37%(5577/87 607)、20.23%(229/1132).결론 산동성지방성불중독병정잉연비교엄중,방치형세의연비교엄준,수진일보가대방치력도.
Objective To investigate the current status of endemic fluorosis in Shandong province, and to provide scientific evidence for the development of control strategies. Methods According to "The National Technical Scheme for Endemic Disease Control in 2007", 19 counties were chosen to carry out the epidemiological investigation in 2008. Water and urinary fluoride were determined by F-ion selective electrode, dental fluorosis of children aged 8 to 12 were diagnosed by Dean method and skeletal fluorosis of adults over the age of 16 were examined clinically and by X-rays. Results In 19 counties, 186 villages were surveyed, 44 villages were found with mean water fluoride ≤ 1.00 mg/L, accounting for 23.66%(44/186);the value ＞ 1.00 mg/L in 142 villages,accounting for 76.34% (142/186);maximum water fluoride 8.88 mg/L. Total detection rate of dental fluorosis of children aged 8 to 12 was 66.35% (4518/6809), dental fluorosis index was 1.55, and defect rate was 15.39%(1048/6809). Children with urinary fluoride ＞ 1.40 mg/L was 83.29%(2149/2580), and the maximum value was 31.92 mg/L. Detection rates of skeletal fluorosis clinically and by X ray among adults over 16 years were 6.37%(5577/87 607) and 20.23% (229/1132), respectively. Conclusions Endemic fluorosis in Shandong province is still serious, prevention efforts need to be further increased.