不同地区母乳中脂肪酸含量及初乳与成熟乳中脂肪酸含量的比较
불동지구모유중지방산함량급초유여성숙유중지방산함량적비교
Comparison of contents of polyunsaturated fatty acids of breast milk among different regions of China and between colostrums and mature milk
  • 万方数据
    中国临床康复 중국림상강복
    CHINESE JOURNAL OF CLINICAL REHABILITATION
    2004年 12期 2389-2391 ,共3页

    张伟利%吴圣楣%钱继红%杨弘伟%庄满利%曹丽娟%乌玉丽%高晓岚

    장위리%오골미%전계홍%양홍위%장만리%조려연%오옥려%고효람

    乳,人/化学%脂肪酸类,不饱和%花生四烯酸%二十二碳六烯酸%α-亚麻酸%亚油酸 乳,人/化學%脂肪痠類,不飽和%花生四烯痠%二十二碳六烯痠%α-亞痳痠%亞油痠
    유,인/화학%지방산류,불포화%화생사희산%이십이탄륙희산%α-아마산%아유산
    背景:人乳中富含的长链多价不饱和脂肪酸(1ong chain polyunsaturated fatty acid,LCPUFAs)对婴儿的脑和视网膜的发育有着非常重要的作用,因此了解母乳中这些脂肪酸的含量十分必要.目的:研究中国不同地区母乳中多不饱和脂肪酸(polyunsaturatedfatty acid,PUFA)含量的差别.设计:横断面研究.地点、对象和方法:选择上海市区和郊区以及浙江省舟山群岛3个地区的健康产妇共196例,其中上海市区产妇60例,上海郊区(崇明县)产妇40例,浙江省舟山群岛产妇96例.采用石英毛细管柱气相色谱法对母乳中PUFA的含量进行了测定.主要观察指标:上海市区、上海郊区和浙江舟山地区母乳中脂肪酸的含量以及初乳与成熟乳中脂肪酸含量的比较.结果:上海市区产妇成熟母乳中亚油酸的含量[(27.30±5.86)%]显著高于郊区崇明县产妇母乳中亚油酸的含量[(20.18±3.86)%],差异有非常显著性意义(t=6.770,P＜0.001),也显著高于浙江舟山地区成熟母乳中亚油酸的含量[(19.75±3.33)%](t=7.460,P＜0.001).而母乳中二十二碳六烯酸(docosahexaenoic acid,DHA)的含量在浙江舟山地区[(0.68±0.23)%]显著高于上海市区[(0.42+0.19)%],差异有非常显著性意义(t=6.203,P＜0.001)和上海郊区母乳中DHA的含量[(0.42±0.16)%],差异有非常显著性意义(t=5.902,P＜0.001).母乳中α-亚麻酸和花生四烯酸(arachidonic acid,AA)的含量在上海市区和郊县以及与浙江舟山地区之间差别无显著性意义(P＞0.05).初乳中AA和DHA的含量,分别为(0.77±0.15)%和(0.80±0.26)%,显著高于成熟乳中AA和DHA的含量[分别为(0.57±0.11)%,(0.68±0.23)%]差异有显著性意义(t=7.248,P＜0.001;t=2.236,P＜0.05).结论:不同地区由于饮食习惯不同,母乳中这些PUFA含量有较大差别.浙江舟山群岛居民由于膳食中鱼和海产类食物较多,故母乳中DHA 的含量较上海地区明显高,但亚油酸的含量却明显低于上海市区.
    배경:인유중부함적장련다개불포화지방산(1ong chain polyunsaturated fatty acid,LCPUFAs)대영인적뇌화시망막적발육유착비상중요적작용,인차료해모유중저사지방산적함량십분필요.목적:연구중국불동지구모유중다불포화지방산(polyunsaturatedfatty acid,PUFA)함량적차별.설계:횡단면연구.지점、대상화방법:선택상해시구화교구이급절강성주산군도3개지구적건강산부공196례,기중상해시구산부60례,상해교구(숭명현)산부40례,절강성주산군도산부96례.채용석영모세관주기상색보법대모유중PUFA적함량진행료측정.주요관찰지표:상해시구、상해교구화절강주산지구모유중지방산적함량이급초유여성숙유중지방산함량적비교.결과:상해시구산부성숙모유중아유산적함량[(27.30±5.86)%]현저고우교구숭명현산부모유중아유산적함량[(20.18±3.86)%],차이유비상현저성의의(t=6.770,P＜0.001),야현저고우절강주산지구성숙모유중아유산적함량[(19.75±3.33)%](t=7.460,P＜0.001).이모유중이십이탄륙희산(docosahexaenoic acid,DHA)적함량재절강주산지구[(0.68±0.23)%]현저고우상해시구[(0.42+0.19)%],차이유비상현저성의의(t=6.203,P＜0.001)화상해교구모유중DHA적함량[(0.42±0.16)%],차이유비상현저성의의(t=5.902,P＜0.001).모유중α-아마산화화생사희산(arachidonic acid,AA)적함량재상해시구화교현이급여절강주산지구지간차별무현저성의의(P＞0.05).초유중AA화DHA적함량,분별위(0.77±0.15)%화(0.80±0.26)%,현저고우성숙유중AA화DHA적함량[분별위(0.57±0.11)%,(0.68±0.23)%]차이유현저성의의(t=7.248,P＜0.001;t=2.236,P＜0.05).결론:불동지구유우음식습관불동,모유중저사PUFA함량유교대차별.절강주산군도거민유우선식중어화해산류식물교다,고모유중DHA 적함량교상해지구명현고,단아유산적함량각명현저우상해시구.
    BACKGROUND: Long chain polyunsaturated fatty acid of breast milk is very important to the brain and retinal development of infants, so it is very necessary to study the contents of the fatty acid.OBJECTIVE: To explore the contents of polyunsaturated fatty acids (PUFAs) in human breast milk from different regions of China.DESIGN: Cross-sectional study.SETTING, PARTICIPANTS and INTERVENTION: Of the 196 human milk samples selected, 60 samples were obtained from healthy postpartum women in Shanghai urban districts, 40 from women of Shanghai suburb (Chongming County) and 96 from women of Zhoushan Islands, Zhejiang Province. The PUFA composition in human milk was analyzed by gas chromatograph fitted with a quartz capillary column.MAIN OUTCOME MEASURES: The fatty acid composition of human milk from women from the 3 regions; comparison in the composition between colostrum and mature breast milk from the 3 regions.RESULTS: The content of linoleic acid(LA) in the mature breast milk from Shanghai urban women was(27.30 + 5.86)%, significantly higher than that from Shanghai suburban women[ (20. 18 ± 3.86)% ], ( t = 6. 7699, P ＜0. 001) and Zhonshan Islands women[ (19.75 ±3.33)% ], ( t =7. 4599, P ＜ 0. 001), whereas the docosahexaenoic acid (DHA) content in the mature breast milk from Zhoushan Islands women was (0. 68 ± 0. 23)%, significantly higher than that from Shanghai urban women[(0.42+0.19)% ], (t=6. 2031, P ＜ 0. 001) and Shanghai suburban women[(0. 42 ±0. 16)% ],(t=5.9015, P ＜ 0.001) . There were no significant differences of α-linolenic acid(LNA) and arachidonic acid(AA) contents in the mature breast milk among the three regions. The contents of AA and DHA in colostrum were(0.77 ±0. 15)% and (0. 80 ±0. 26)%, respectively, which were significantly higher than those in mature breast milk[ (0. 57 ± 0. 11 )%,t =7. 2484, P ＜0.001 and (0.68 ±0. 23)%, t =2. 2358, P ＜0.05].CONCLUSION: The differences in PUFA composition of breast milk may be attributed to the different dietary habits in different countries and regions. More fish and seafood intake by Zhoushan Islands women may account for the relatively higher DHA level in their milk. Higher levels of AA and DHA in colostrum are much beneficial to the growth and development of newborn infants. Therefore, breast-feeding should be advocated.
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