天然产物研究与开发
天然產物研究與開髮
천연산물연구여개발
NATURAL PRODUCT RESEARCH AND DEVELOPMENT
2010年
2期
181-184
,共4页
景莹%张晓琦%韩伟立%张云天%叶文才
景瑩%張曉琦%韓偉立%張雲天%葉文纔
경형%장효기%한위립%장운천%협문재
蒙桑%化学成分%多羟基生物碱%2,4,2′,4′-tetrahydroxychalcone
矇桑%化學成分%多羥基生物堿%2,4,2′,4′-tetrahydroxychalcone
몽상%화학성분%다간기생물감%2,4,2′,4′-tetrahydroxychalcone
Moats mongolica%Chemical constituent%nolvhvdroxvlated alkaloid%2,4,2′,4′,-tctrahvdroxvchalcone
运用大孔吸附树脂、离子交换树脂、硅胶和Sephadex LH-20等色谱方法对蒙桑Morus mongolica叶的化学成分进行分离纯化,分离得到了10个化合物.通过NMR等波谱技术确定化合物的结构,分别鉴定为1-脱氧野尻霉素(1)、Fagomine(2)、肌醇c(3)、moracin M(4)、moracin M3-O-β-D-glucopyranoside(5)、umbelliferone(6)、scopoletin(7)、syringaresinol(8)、2,4,2′,4′-tetrahydroxychaleone(9)和胡萝卜苷(10).其中化合物2、3、5～10为首次从该植物中分离得到的,化合物9为一新天然产物.
運用大孔吸附樹脂、離子交換樹脂、硅膠和Sephadex LH-20等色譜方法對矇桑Morus mongolica葉的化學成分進行分離純化,分離得到瞭10箇化閤物.通過NMR等波譜技術確定化閤物的結構,分彆鑒定為1-脫氧野尻黴素(1)、Fagomine(2)、肌醇c(3)、moracin M(4)、moracin M3-O-β-D-glucopyranoside(5)、umbelliferone(6)、scopoletin(7)、syringaresinol(8)、2,4,2′,4′-tetrahydroxychaleone(9)和鬍蘿蔔苷(10).其中化閤物2、3、5～10為首次從該植物中分離得到的,化閤物9為一新天然產物.
운용대공흡부수지、리자교환수지、규효화Sephadex LH-20등색보방법대몽상Morus mongolica협적화학성분진행분리순화,분리득도료10개화합물.통과NMR등파보기술학정화합물적결구,분별감정위1-탈양야고매소(1)、Fagomine(2)、기순c(3)、moracin M(4)、moracin M3-O-β-D-glucopyranoside(5)、umbelliferone(6)、scopoletin(7)、syringaresinol(8)、2,4,2′,4′-tetrahydroxychaleone(9)화호라복감(10).기중화합물2、3、5～10위수차종해식물중분리득도적,화합물9위일신천연산물.
Chemical constituents of the leaves of Morus mongolica were isolated and pured by ion-exchange resin,silica gel,ODS and Sephadex LH-20 column chromatographies.Their structures were elucidated on the basis of physico-chemical properties and spectral data.Ten compounds were identified as 1-deoxynojirimycin(1),fagomine(2),myo-inositol(3),moraein M(4),moraein M 3-O-～-D-glueopyranoside(5),umbelliferone(6),seopolefin(7),syringaresinol(8),2,4,2′,4′-tetrahydroxychalcone(9)and dausterd(10),respectively.Compounds 2,3,5～10 were isolated from this plant for the first time,and compound9 is a new natural product.
