CAJ | 학술논문

目的应用回声跟踪( echo tracking,ET)技术对受试者双侧颈动脉参数进行分析,定量评价高压氧干预对颈动脉弹性的影响.方法 41例行高压氧治疗的患者为高压氧组,20名健康者为高气压组,另20名健康者为高流量组.前2组于进舱前及出舱后即刻、高流量组于吸氧前及吸氧后即刻,应用ET对双侧颈动脉弹性进行检测,检测参数包括血管的压力-应变弹性系数(Ep)、硬化参数(β)及血管顺应性(AC).结果高压氧组干预后Ep[(112.38±50.94)kPa]及β值(8.29±3.66)较干预前均减小(129.04±52.4)kPa,(9,75±3.83),AC值增大[干预前(0.86±0.34) mm2/kPa,干预后(0.99±0.45)mm2/kpa],差异均有统计学意义(P＜0.01),高气压组干预后β及Ep较值进舱前减小,AC值较进舱前增加,差异均有统计学意义(P＜0.01或P＜0.05)；高流量组吸氧前后Ep、β及AC值差异均无统计学意义(P＞0.05);年龄＜40岁的高压氧组及高气压组干预后Ep、β及AC值均有改善,且高压氧组较高气压组改善更明显,2组比较差异有统计学意义(P＜0.05或P＜0.01).结论高压氧干预即刻即可改善颈动脉弹性.
목적 응용회성근종( echo tracking,ET)기술대수시자쌍측경동맥삼수진행분석,정량평개고압양간예대경동맥탄성적영향.방법 41례행고압양치료적환자위고압양조,20명건강자위고기압조,령20명건강자위고류량조.전2조우진창전급출창후즉각、고류량조우흡양전급흡양후즉각,응용ET대쌍측경동맥탄성진행검측,검측삼수포괄혈관적압력-응변탄성계수(Ep)、경화삼수(β)급혈관순응성(AC).결과 고압양조간예후Ep[(112.38±50.94)kPa]급β치(8.29±3.66)교간예전균감소(129.04±52.4)kPa,(9,75±3.83),AC치증대[간예전(0.86±0.34) mm2/kPa,간예후(0.99±0.45)mm2/kpa],차이균유통계학의의(P＜0.01),고기압조간예후β급Ep교치진창전감소,AC치교진창전증가,차이균유통계학의의(P＜0.01혹P＜0.05)；고류량조흡양전후Ep、β급AC치차이균무통계학의의(P＞0.05);년령＜40세적고압양조급고기압조간예후Ep、β급AC치균유개선,차고압양조교고기압조개선경명현,2조비교차이유통계학의의(P＜0.05혹P＜0.01).결론 고압양간예즉각즉가개선경동맥탄성.
Ohjectlve To evaluate quantitatively the effect of hyperbaric oxygen (HBO) on carotid artery elasticity with bilateral carotid artery parameters by echo tracking (ET).Methods Forty-one patients who received HBO therapy were assigned to the HBO group ( group 1 ),20 healthy subjects assigned to the hyperbaric air group ( group 2) and still another 20 healthy subjects were assigned to the high-flow oxygen therapy group ( group 3).The patients of group 1 breathed pure oxygen at 0.20 MPa for a duration of 60 min,and the subjects of group 3 breathed pure oxygen at normal pressure also for a duration of 60 rmin.For the first 2 groups,bilateral carotid artery elasticity was measured with ET,at a time right before entrance into the chamber and right after exit from the chamber; and for group 3,measurement was made with ET,at a time right before oxygen breathing and right after oxygen breathing.The measured data included vascular pressure-strain elasticity modulus (Ep),data of artery stiffness (β) and artery compliance (AC).Results For the HBO group,when patients came out of the chamber,Ep and β levels were significantly decreased,while AC data were significantly increased,with statistical significance,when compared with that of pre-HBO therapy[preintervention of HBO: Ep ( 129.04 ± 52.47 ) kPa,β: (9.75 ± 3.83),AC: ( 0,86 ± 0.34 ) mm2/kPa; postintervention of HBO: Ep: ( 112.38 ± 50.94 ) kPa,β: ( 8.29 ± 3.66 ),AC: (0.99 ± 0.45 ) mm2/kPa ]( P ＜0.0l ).For the hyperbaric air group,when subjects came out of the chamber,Ep and β levels were decreased,while AC data were increased,all with statistical significance,when compared with that before entrance into the chamber (P ＜ 0.0 l or P ＜ 0.05 ).For the high-flow oxygen therapy group,no differences could be detected in Ep,β and AC data measured both before and after oxygen breathing,without statistical significance ( P ＞0.05).For those in group 1 and group 2,with an age of less than 40,Ep,β and AC data all improved,when they came out of the chamber (P ＜0.01 or P ＜0,05 ),with HBO group having more significant improvement than the hyperbaric air group.And statistical significance could be noted,when a comparison was madebetween the two ( P ＜ 0.01 or P ＜ 0.05 ).Conclusions HBO intervention could improve carotid artery elasticity.