CAJ | 학술논문

目的探讨控制气管导管套囊压力对全麻手术患者气管插管相关性并发症的影响.方法本研究为前瞻性、多中心、随机、双盲研究.择期拟行全麻手术患者509例,ASA分级Ⅰ或Ⅱ级,年龄11～89岁,体重35～92kg,性别不限,随机分为2组:对照组(C组)和套囊压力测定组(CPM组),记录手术时间和带管时间.各组随机选取20例带管时间120～180 min的患者,于拔除气管导管时行纤维支气管镜检查.拔除气管导管后24 h内随访咳嗽及痰中带血等气管插管相关性并发症的发生情况.结果两组患者年龄、性别构成比、手术时间及带管时间差异无统计学意义(P＞0.05).与C组比较,CPM组患者咽喉痛及痰中带血的发生率降低(P＜0.05);随带管时间延长,C组咽喉痛及痰中带血的发生率均升高,CPM组仅咽喉痛的发生率升高(P＜0.01).纤维支气管镜检查可见气管粘膜不同程度损伤,C组较CPM组严重.结论控制气管导管套囊压力有助于减少全麻手术患者术后气管插管相关性并发症的发生.
목적 탐토공제기관도관투낭압력대전마수술환자기관삽관상관성병발증적영향.방법 본연구위전첨성、다중심、수궤、쌍맹연구.택기의행전마수술환자509례,ASA분급Ⅰ혹Ⅱ급,년령11～89세,체중35～92kg,성별불한,수궤분위2조:대조조(C조)화투낭압력측정조(CPM조),기록수술시간화대관시간.각조수궤선취20례대관시간120～180 min적환자,우발제기관도관시행섬유지기관경검사.발제기관도관후24 h내수방해수급담중대혈등기관삽관상관성병발증적발생정황.결과 량조환자년령、성별구성비、수술시간급대관시간차이무통계학의의(P＞0.05).여C조비교,CPM조환자인후통급담중대혈적발생솔강저(P＜0.05);수대관시간연장,C조인후통급담중대혈적발생솔균승고,CPM조부인후통적발생솔승고(P＜0.01).섬유지기관경검사가견기관점막불동정도손상,C조교CPM조엄중.결론 공제기관도관투낭압력유조우감소전마수술환자술후기관삽관상관성병발증적발생.
Objective To investigate the incidence of postoperative intubation-related complications and the need for measurement and adjustment of cuff-pressure of endotracheal tube. Methods Five hundred and nine patients of either sex undergoing elective surgery under general anesthesia with tracheal intubation were divided into 2 groups: control group (group C)and cuff-pressure measured group (group CPM). Operation time and duration of endotracheal tube were recorded. Twenty patients with the duration of endotracheal tube 120-180 min in each group were selected. Their tracheal mucous membrane was examined by fiberoptic bronchoscopy at the time of withdrawal of endotracheal tube. Postoperative complications including cough and bloody sputum were also recorded at 24 h after extubation. Results The two groups were comparable with respect to age, sex, operation time and the duration of endotracheal tube. The incidence of sore throat and bloody sputum was significantly higher in group C than in CPM group. The incidence of sore throat and bloody sputum was significantly increased as the duration of endotracheal tube was prolonged in control group while in CPM group only the incidence of sore throat was increased. Varying degrees of injuries to tracheal mucous membrane were observed with fiberoptic bronchoscope.The injuries were more serious in group C than in CPM group. Conclusion Measurement of intracuff pressure is helpful for reducing the tracheal intubation-related complications.