中国中西医结合杂志(英文版)
中國中西醫結閤雜誌(英文版)
중국중서의결합잡지(영문판)
CHINESE JOURNAL OF INTEGRATED TRADITIONAL AND WESTERN MEDICINE
2001年
4期
283-287
,共5页
许勇钢%麻柔%胡乃平%刘锋%杨经敏%马玲%胡晓梅
許勇鋼%痳柔%鬍迺平%劉鋒%楊經敏%馬玲%鬍曉梅
허용강%마유%호내평%류봉%양경민%마령%호효매
Fuzheng Kangbai Granule%minimal residual leukemia%immune function
To observe the effects of Fuzheng Kangbai Granule (FZKBG) on immune function and survival time in minimal residual leukemia (MRL) model mice and explore its mechanism. Methods: MRL model mice were established by hypodermic inoculation with L7212 cells 1×106 following intraperitoneal injection of cytoxan (CTX) 250 mg/kg 3 days later, and divided into the control group and FZKBG treated group. The changes of T-lymphocyte subsets, including CD3+, CD4+ and CD8+, and the survival time in model mice were observed. Results: Compared with the control, FZKBG could obviously increase both the percentage and absolute value of CD3+ and CD4+ lymphocytes and prolong the survival time of model mice, the prolongation rate being 29.6% - 60.4%. Conclusion: FZKBG could markedly prolong the survival time of MRL mice, and its mechanism might be through elevating the immunologic function and inhibiting the leukemia cells in model mice.
