CAJ | 학술논문

目的探讨发生在重症监护病房(ICU)内嗜麦芽窄食单胞菌医院感染肺炎的临床特点及药物敏感性.方法对本院重症监护病房2003年1月至2007年12月出现的47例嗜麦芽窄食单胞菌医院感染肺炎患者的资料作回顾性分析.结果全部患者均有基础疾病,广谱抗生素的使用、ICU内的停留时间、人工气道、机械通气、深静脉置管、免疫抑制剂的使用等与嗜麦芽窄食单胞菌医院感染肺炎的发生有明显的相关性;嗜麦芽窄食单胞菌仅对复方新诺明、替卡西林/克拉维酸、头孢哌酮/舒巴坦、左氧氟沙星、环丙沙星较为敏感,敏感率在80.85%～61.7%之间.结论嗜麦芽窄食单胞菌主要引起呼吸系统感染,该菌耐药情况十分严重.缩短住院和入住ICU时间、尽量减少有创操作、合理应用抗生素是减少感染发生的重要措施.
목적 탐토발생재중증감호병방(ICU)내기맥아착식단포균의원감염폐염적림상특점급약물민감성.방법 대본원중증감호병방2003년1월지2007년12월출현적47례기맥아착식단포균의원감염폐염환자적자료작회고성분석.결과 전부환자균유기출질병,엄보항생소적사용、ICU내적정류시간、인공기도、궤계통기、심정맥치관、면역억제제적사용등여기맥아착식단포균의원감염폐염적발생유명현적상관성;기맥아착식단포균부대복방신낙명、체잡서림/극랍유산、두포고동/서파탄、좌양불사성、배병사성교위민감,민감솔재80.85%～61.7%지간.결론 기맥아착식단포균주요인기호흡계통감염,해균내약정황십분엄중.축단주원화입주ICU시간、진량감소유창조작、합리응용항생소시감소감염발생적중요조시.
Objective To investigate the clinical characteristics and resistance of Stenotrophomona maltophila in intensive care unit.Methods 47 cases with nosocomial pneumonia by Stenotrophomona maltophila in intensive care unit from Jan 2003 to Nov 2007 were studied retrospectively.Results All patients had clinical symptoms,treatment with broad spectrum of antibiotics,the length of stay in ICU,artificial airways,mechanical ventilation,central venous catheter and usage of immunosuppressor,all the factor were obviously related with Stenotrophomona maltophila;SMITMP,ticarcillin/clavulanate,cefoperazone/sulbactam,levo-floxacin,ciprofloxacin were higher susceptive to S: maltophila,in range of 80.85%～61.7%.Conclusion The drug resistance in this kind of bacterium is extremely severe,and it mainly cause the infection of respiratory tract.Decreasing days being in hospital and ICU,using antibiotic reasonably,reducing invasive operation may decrease the infection of S.maltophila.