中华泌尿外科杂志
中華泌尿外科雜誌
중화비뇨외과잡지
CHINESE JOURNAL OF UROLOGY
2010年
11期
748-751
,共4页
刘光香%郭宏骞%李笑弓%刘铁石%张士伟%甘卫东%燕翔%纪长威%汪维%曾令奇
劉光香%郭宏鶱%李笑弓%劉鐵石%張士偉%甘衛東%燕翔%紀長威%汪維%曾令奇
류광향%곽굉건%리소궁%류철석%장사위%감위동%연상%기장위%왕유%증령기
射频消融%孤立肾%癌,肾细胞
射頻消融%孤立腎%癌,腎細胞
사빈소융%고립신%암,신세포
Radiofrequency ablation%Solitary kidney%Carcinoma%renal cell
目的 探讨射频消融治疗功能性孤立肾肾细胞癌的可行性及临床疗效. 方法对5例功能性孤立肾肾细胞癌患者实施射频消融治疗.B超、CT扫描检查肿瘤位于左肾3例,右肾2例.肿瘤最大径3.0~6.0 cm,未发现远处转移灶.T1aN0M0 3例,T1bN0M0 2例.术前常规实验室检查,术后采用增强CT扫描(CECT)、超声造影(CEUS)定期随访. 结果 5例平均手术时间(100.0±28.5)min,平均出血量(95.0±30.5)ml,术中、术后均未输血.术后均有发热,体温(38.2±0.7)℃.术后1周CEUS示5例肾癌病灶均完全消融.血红蛋白(Hb)、血肌酐(SCr)、患侧ECT-肾小球滤过率(ECT-GFR)和肌酐清除率(Ccr)较术前均无明显变化(P>0.05).随访5~19个月,中位数11.5个月,均未见复发,SCr维持(87.5±17.3)μmol/L. 结论 射频消融治疗功能性孤立肾肾细胞癌具有保留肾单位、并发症少及恢复快等优势,是目前治疗功能性孤立肾肾细胞癌一种可选择的方法.
目的 探討射頻消融治療功能性孤立腎腎細胞癌的可行性及臨床療效. 方法對5例功能性孤立腎腎細胞癌患者實施射頻消融治療.B超、CT掃描檢查腫瘤位于左腎3例,右腎2例.腫瘤最大徑3.0~6.0 cm,未髮現遠處轉移竈.T1aN0M0 3例,T1bN0M0 2例.術前常規實驗室檢查,術後採用增彊CT掃描(CECT)、超聲造影(CEUS)定期隨訪. 結果 5例平均手術時間(100.0±28.5)min,平均齣血量(95.0±30.5)ml,術中、術後均未輸血.術後均有髮熱,體溫(38.2±0.7)℃.術後1週CEUS示5例腎癌病竈均完全消融.血紅蛋白(Hb)、血肌酐(SCr)、患側ECT-腎小毬濾過率(ECT-GFR)和肌酐清除率(Ccr)較術前均無明顯變化(P>0.05).隨訪5~19箇月,中位數11.5箇月,均未見複髮,SCr維持(87.5±17.3)μmol/L. 結論 射頻消融治療功能性孤立腎腎細胞癌具有保留腎單位、併髮癥少及恢複快等優勢,是目前治療功能性孤立腎腎細胞癌一種可選擇的方法.
목적 탐토사빈소융치료공능성고립신신세포암적가행성급림상료효. 방법대5례공능성고립신신세포암환자실시사빈소융치료.B초、CT소묘검사종류위우좌신3례,우신2례.종류최대경3.0~6.0 cm,미발현원처전이조.T1aN0M0 3례,T1bN0M0 2례.술전상규실험실검사,술후채용증강CT소묘(CECT)、초성조영(CEUS)정기수방. 결과 5례평균수술시간(100.0±28.5)min,평균출혈량(95.0±30.5)ml,술중、술후균미수혈.술후균유발열,체온(38.2±0.7)℃.술후1주CEUS시5례신암병조균완전소융.혈홍단백(Hb)、혈기항(SCr)、환측ECT-신소구려과솔(ECT-GFR)화기항청제솔(Ccr)교술전균무명현변화(P>0.05).수방5~19개월,중위수11.5개월,균미견복발,SCr유지(87.5±17.3)μmol/L. 결론 사빈소융치료공능성고립신신세포암구유보류신단위、병발증소급회복쾌등우세,시목전치료공능성고립신신세포암일충가선택적방법.
Objective To evaluate the clinical feasibility of radiofrequency ablation (RFA) for renal cell carcinoma in functional solitary kidney. Methods Five selected cases of primary renal cell carcinoma in a functional solitary kidney were retrospective analyzed. Three cases of left renal cell carcinoma and 2 cases of right renal cell carcinoma were diagnosed by B ultrasound and CT scanning. The maximum diameter of the tumors were 3.0- 6.0 cm. Three cases of which were T1a N0 M0 and the others Were T1bN0M0. All patients were followed up with enhanced-CT and contrast-enhanced ultrasonography. Results The mean time of the operation was 100.0+28.5 min, and the mean blood loss was 95.0±30.5 ml. No patients accepted blood transfusion post-operation. All patients after operation had fever (38.2±0. 7 ℃ ). All the lesions were completely ablated on contrast-enhanced ultrasonography. There was no statistic change of hemoglobin, serum creatinine (SCr), ECT-GFR and creatinine clearance after operation (P>0.05). All of the 5 cases survived. No recurrence were found by enhanced-CT and contrast-enhanced ultrasonography and SCr was retaining in the normal level during follow-ups (median, 11.5 months). Conclusion Radiofrequency ablation for renal cell carcinoma in a functional solitary kidney could be a treatment choice with a relatively low incidence of complications.