CAJ | 학술논문

将离子液体(n-丁基吡啶六氟磷酸盐,[BuPy][PF6])与石墨粉混合,制备了离子液体修饰碳糊电极(CILE).在0.1mol/L醋酸盐缓冲溶液中(pH 4.7),采用循环伏安法(CV)、方波伏安法(SWV)及计时库仑分析法研究了对乙酰氨基酚的电化学行为.结果表明:CILE对对乙酰氨基酚的氧化还原具有明显的电催化作用；在0.1 V/s扫速下,对乙酰氨基酚的氧化还原峰峰电位差(△Ep)为88mV；扩散系数(D)为1.214×10-7 cm2/s.对乙酰氨基酚的氧化峰电流与其浓度在0.5～10.0μmol/L范围内呈线性关系(r＝0.998 8),检出限为0.01 μmol/L( S/N＝3).该修饰电极成功用于片剂与尿样中对乙酰氨基酚含量的检测,且具有制作成本低、稳定性好、易于重复和制备等特点.
장리자액체(n-정기필정륙불린산염,[BuPy][PF6])여석묵분혼합,제비료리자액체수식탄호전겁(CILE).재0.1mol/L작산염완충용액중(pH 4.7),채용순배복안법(CV)、방파복안법(SWV)급계시고륜분석법연구료대을선안기분적전화학행위.결과표명:CILE대대을선안기분적양화환원구유명현적전최화작용；재0.1 V/s소속하,대을선안기분적양화환원봉봉전위차(△Ep)위88mV；확산계수(D)위1.214×10-7 cm2/s.대을선안기분적양화봉전류여기농도재0.5～10.0μmol/L범위내정선성관계(r＝0.998 8),검출한위0.01 μmol/L( S/N＝3).해수식전겁성공용우편제여뇨양중대을선안기분함량적검측,차구유제작성본저、은정성호、역우중복화제비등특점.
A carbon ionic liquid electrode (CILE),which was fabricated by mixing hydrophobic room temperature ionic liquid,n-butyl pyridinium hexafluophosphate ( [ BuPy ] [ PF6 ] ),with graphite powder,was used to investigate the electrochemical behaviors of paracetamol in 0.1 mol/L acetate buffer solution ( pH 4.7 ) by cyclic voltammetry (CV),square wave voltammetry (SWV) and chronocoulometry.The peak-to-peak potential separation (△Ep,) of paracetamol was 0.088 V with scan rate of 0.1 V/s.The results showed that CILE exhibited better electrocatalysis for redox of paracetamol.Diffusion coefficient (D) was calculated as 1.214 × 10-7 cm2/s.The oxidation peak current versus concentration of paracetamol at CILE showed linearity in the range of 0.5-10.0 μmol/L (r ＝0.998 8) with a detection limit of 0.01 μmot/L ( S/N ＝ 3).The proposed method was applied to determination of paracetamol in tablets and urine samples successfully.In addition,CILE was inexpensive,stable,repeatable and easy to be fabricated.