中华放射医学与防护杂志
中華放射醫學與防護雜誌
중화방사의학여방호잡지
Chinese Journal of Radiological Medicine and Protection
2012年
3期
297-300
,共4页
吴晨彬%吴君心%徐鹭英%林少俊%柏朋刚%张秀春%潘建基
吳晨彬%吳君心%徐鷺英%林少俊%柏朋剛%張秀春%潘建基
오신빈%오군심%서로영%림소준%백붕강%장수춘%반건기
海马结构%鼻咽癌%调强放疗
海馬結構%鼻嚥癌%調彊放療
해마결구%비인암%조강방료
Hippocampal formation%Nasopharyngeal carcinoma%Intensity modulated radiotherapy
目的 分析鼻咽癌调强放疗中海马结构的受照剂量及相关影响因素.方法 回顾性分析59例鼻咽癌的调强放疗计划,比较不同临床分期鼻咽癌的海马结构受照剂量及特点.结果 59例鼻咽癌患者的海马结构受照剂量受T分期影响明显,Dmax11.1 ～78.2 Gy,Dmean3.2 ～44.6 Gy,T1 ～T4期海马结构受照剂量(Dmax和Dmean)差异均有统计学意义,Dmax(F=24.2,P＜0.05)、Dmean(P=16.3,P＜0.05).其中T3、T4期病例平均受照剂量和体积明显高于T1、T2期,Dmax、Dmean分别为(58.6±14.8)Gy、(20.9±19.3) Gy和(40.8±9.4) Gy、(12.5±5.1) Gy.结论 鼻咽癌调强放疗中,海马结构可能受到较大剂量的照射,肿瘤T分期是重要的影响因素,特别在T3-4期病例放疗中值得关注.
目的 分析鼻嚥癌調彊放療中海馬結構的受照劑量及相關影響因素.方法 迴顧性分析59例鼻嚥癌的調彊放療計劃,比較不同臨床分期鼻嚥癌的海馬結構受照劑量及特點.結果 59例鼻嚥癌患者的海馬結構受照劑量受T分期影響明顯,Dmax11.1 ～78.2 Gy,Dmean3.2 ～44.6 Gy,T1 ～T4期海馬結構受照劑量(Dmax和Dmean)差異均有統計學意義,Dmax(F=24.2,P＜0.05)、Dmean(P=16.3,P＜0.05).其中T3、T4期病例平均受照劑量和體積明顯高于T1、T2期,Dmax、Dmean分彆為(58.6±14.8)Gy、(20.9±19.3) Gy和(40.8±9.4) Gy、(12.5±5.1) Gy.結論 鼻嚥癌調彊放療中,海馬結構可能受到較大劑量的照射,腫瘤T分期是重要的影響因素,特彆在T3-4期病例放療中值得關註.
목적 분석비인암조강방료중해마결구적수조제량급상관영향인소.방법 회고성분석59례비인암적조강방료계화,비교불동림상분기비인암적해마결구수조제량급특점.결과 59례비인암환자적해마결구수조제량수T분기영향명현,Dmax11.1 ～78.2 Gy,Dmean3.2 ～44.6 Gy,T1 ～T4기해마결구수조제량(Dmax화Dmean)차이균유통계학의의,Dmax(F=24.2,P＜0.05)、Dmean(P=16.3,P＜0.05).기중T3、T4기병례평균수조제량화체적명현고우T1、T2기,Dmax、Dmean분별위(58.6±14.8)Gy、(20.9±19.3) Gy화(40.8±9.4) Gy、(12.5±5.1) Gy.결론 비인암조강방료중,해마결구가능수도교대제량적조사,종류T분기시중요적영향인소,특별재T3-4기병례방료중치득관주.
Objective To evaluate the dosimetric characteristics of hippocampal formation (HF) in the intensity-modulated radiotherapy (IMRT) for nasopharyngeal carcinoma (NPC).Methods Fifty-nine NPC patients underwent IMRT.Simultaneous integrated boost technology was used to determine the doses for the target areas.The dose ranges of the HF were collected by dose-volume histogram.The influence of T stage on the exposure doses ( Dmax,Dmean,D20,V10,V20,V30,and V40 ) were compared.Results The maximum dose for the HF (Dmax) ranged from 11.1 to 78.2 Gy(F =24.2,P ＜0.05) and the Dmean ranged from 3.2 to 44.6 Gy ( F =16.3,P ＜ 0.05 ).The Dmax and Dmean of the T1-2 stage patients were (40.8 ±9.4) Gy and ( 12.5 ±5.1 ) Gy,respectively,both significantly lower than those of the T3-4 stage patients [ (58.6± 14.8) Gy,(20.9± 9.3 ) Gy].The mean exposed volume of the T4 stage patients was significantly larger than that of the T1 and T2 stages patients.Conclusions In the IMRT of NPC,the HF receives rather high irradiation dose.T stage is the main factor influencing the dose,especially T3 and T4 stages deserve serious attention.
