中华妇产科杂志
中華婦產科雜誌
중화부산과잡지
CHINESE JOUNAL OF OBSTETRICS AND GYNECOLOGY
2011年
3期
181-183
,共3页
江楠%王丽萍%常永富%付伟平
江楠%王麗萍%常永富%付偉平
강남%왕려평%상영부%부위평
胚胎移植%生殖技术,辅助%妊娠率%妊娠,多胎%低温保存
胚胎移植%生殖技術,輔助%妊娠率%妊娠,多胎%低溫保存
배태이식%생식기술,보조%임신솔%임신,다태%저온보존
Embryo transfer%Reproductive techniques,assisted%Pregnancy rate%Pregnancy,multiple%Cryopreservation
目的 探讨年龄<35岁妇女,减少冻融胚胎移植数量对移植结局的影响.方法 77例年龄<35岁患者共进行冻融胚胎移植90个周期,采用慢速冷冻快速复苏法对胚胎进行冷冻及解冻,移植胚胎数量分别为2个胚胎(48个周期)和3个胚胎(42个周期),比较其移植结局,包括临床妊娠率、胚胎植入率和多胎妊娠率等.结果 移植2个胚胎患者的胚胎复苏存活率、优质胚胎率、临床妊娠率、胚胎植入率和多胎妊娠率分别为88.9%、89.6%、37.5%、26.0%、38.9%,移植3个胚胎患者分别为88.1%、81.0%、42.9%、18.3%、16.7%;两者间分别比较,差异均无统计学意义(P>0.05).但移植2个胚胎者中无三胎妊娠发生,而移植3个胚胎者中发生2次三胎妊娠.结论 冻融胚胎移植周期中,如果胚胎质量良好,年龄<35岁妇女移植胚胎数量从3个减少至2个,并不会明显降低临床妊娠率,同时可减少三胎妊娠的发生.
目的 探討年齡<35歲婦女,減少凍融胚胎移植數量對移植結跼的影響.方法 77例年齡<35歲患者共進行凍融胚胎移植90箇週期,採用慢速冷凍快速複囌法對胚胎進行冷凍及解凍,移植胚胎數量分彆為2箇胚胎(48箇週期)和3箇胚胎(42箇週期),比較其移植結跼,包括臨床妊娠率、胚胎植入率和多胎妊娠率等.結果 移植2箇胚胎患者的胚胎複囌存活率、優質胚胎率、臨床妊娠率、胚胎植入率和多胎妊娠率分彆為88.9%、89.6%、37.5%、26.0%、38.9%,移植3箇胚胎患者分彆為88.1%、81.0%、42.9%、18.3%、16.7%;兩者間分彆比較,差異均無統計學意義(P>0.05).但移植2箇胚胎者中無三胎妊娠髮生,而移植3箇胚胎者中髮生2次三胎妊娠.結論 凍融胚胎移植週期中,如果胚胎質量良好,年齡<35歲婦女移植胚胎數量從3箇減少至2箇,併不會明顯降低臨床妊娠率,同時可減少三胎妊娠的髮生.
목적 탐토년령<35세부녀,감소동융배태이식수량대이식결국적영향.방법 77례년령<35세환자공진행동융배태이식90개주기,채용만속냉동쾌속복소법대배태진행냉동급해동,이식배태수량분별위2개배태(48개주기)화3개배태(42개주기),비교기이식결국,포괄림상임신솔、배태식입솔화다태임신솔등.결과 이식2개배태환자적배태복소존활솔、우질배태솔、림상임신솔、배태식입솔화다태임신솔분별위88.9%、89.6%、37.5%、26.0%、38.9%,이식3개배태환자분별위88.1%、81.0%、42.9%、18.3%、16.7%;량자간분별비교,차이균무통계학의의(P>0.05).단이식2개배태자중무삼태임신발생,이이식3개배태자중발생2차삼태임신.결론 동융배태이식주기중,여과배태질량량호,년령<35세부녀이식배태수량종3개감소지2개,병불회명현강저림상임신솔,동시가감소삼태임신적발생.
Objective To study the impact on pregnant outcome of reducing the number of embryos transferred from three to two in women at age less than 35 who received frozen-thawed embryo transfer (FET). Methods The analysis was performed on 90 FET cycles (77 infertile couples,less than 35 years old) with slow-freezing/rapid-thawing method, including 48 cycles with two embryos transferred and 42 cycles with three embryos transferred. The embryo survival rate, high quality embryo rate, clinical pregnancy rate, implantation rate and multiple pregnancies rate were analyzed. Results No significant differences in embryo survival rate (88.9% versus 88.1%), high quality embryo rate (89.6% versus 81.0%), clinical pregnancy rate (37.5% versus 42.9%), implantation rate (26.0% versus 18.3%) and multiple pregnancy rate (38.9% versus 16.7%) were observed between two and three embryos transferred group (all P > 0.05). However, there were 2 triple pregnancies in three embryos transferred group while none in two embryos transferred group. Conclusion Reducing the number of high quality embryos transferred from three to two in women at age of less than 35 years old who received FET,could decrease the incidence of triple pregnancy and keep the similar clinical pregnancy rate.
