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中国药学（英文版） 중국약학（영문판）
JOURNAL OF CHINESE PHARMACEUTICAL SCIENCES
2006年 4期 206-210 ,共5页

金伟%格日立%黄志勤%魏全嘉%包天佑%屠鹏飞

금위%격일립%황지근%위전가%포천우%도붕비

唐古特大黄%4'-羟基苯基-2-丁酮%4'-羟基苯基-2-丁酮-4'-O-β-D-(2"-O-桂皮酰基-6"-O-没食子酰基)-葡萄糖苷%4'-羟基苯基-2-丁酮-4'-O-β-D-(2"-O-没食子酰基-6"-O-(4"'-羟基)-桂皮酰基)-葡萄糖苷唐古特大黃%4'-羥基苯基-2-丁酮%4'-羥基苯基-2-丁酮-4'-O-β-D-(2"-O-桂皮酰基-6"-O-沒食子酰基)-葡萄糖苷%4'-羥基苯基-2-丁酮-4'-O-β-D-(2"-O-沒食子酰基-6"-O-(4"'-羥基)-桂皮酰基)-葡萄糖苷
당고특대황%4'-간기분기-2-정동%4'-간기분기-2-정동-4'-O-β-D-(2"-O-계피선기-6"-O-몰식자선기)-포도당감%4'-간기분기-2-정동-4'-O-β-D-(2"-O-몰식자선기-6"-O-(4"'-간기)-계피선기)-포도당감
Rheum tanguticum Maxim ex Balf.%4-(4'-hydroxyphenyl)-2-butanone%4-(4'-hydroxyphenyl)-2-butanone-4'-O-β-D-(2"-O-cinnamoyl-6"-O-galloyl)-glucopyranoside%4-(4'-hydroxyphenyl)-2-butanone-4'-O-β-D-(2"-O-galloyl-6"-O-p-coumaroyl)-glucopyranoside

目的研究唐古特大黄的化学成分.方法采用多种色谱技术进行分离纯化,应用质谱、核磁等技术确定化合物的结构.结果从唐古特大黄的根和根茎中分离得到β-谷甾醇、大黄酚、芦荟大黄素、大黄素甲醚、大黄酸、大黄素等20个化合物.结论 4'-羟基苯基-2-丁酮(9)、4'-羟基苯基-2-丁酮-4'-O-β-D-(2"-O-桂皮酰基-6"-O-没食子酰基)-葡萄糖苷(12) 和4'-羟基苯基-2-丁酮-4'-O-β-D-(2"-O-没食子酰基-6"-O-(4"'-羟基)-桂皮酰基)-葡萄糖苷(13)为首次从该种植物中分离得到.
목적 연구당고특대황적화학성분.방법 채용다충색보기술진행분리순화,응용질보、핵자등기술학정화합물적결구.결과 종당고특대황적근화근경중분리득도β-곡치순、대황분、호회대황소、대황소갑미、대황산、대황소등20개화합물.결론 4'-간기분기-2-정동(9)、4'-간기분기-2-정동-4'-O-β-D-(2"-O-계피선기-6"-O-몰식자선기)-포도당감(12) 화4'-간기분기-2-정동-4'-O-β-D-(2"-O-몰식자선기-6"-O-(4"'-간기)-계피선기)-포도당감(13)위수차종해충식물중분리득도.
Aim To study the chemical constituents of the root and rhizome of Rheum tanguticum Maxim. ex Balf. Methods Chemical constituents were isolated and purified by many chromatographic methods, and their structures were elucidated by MS, NMR, and others. Results Twenty compounds were isolated and their structures were identified as β-sitosterol, chrysophanol, aloe-emodin, physcion, rhein, emodin, etc. Conclusion Among these compounds, 4-(4'-hydroxyphenyl)-2-butanone, 4-(4'-hydroxyphenyl)-2-butanone-4'-O-β-D-(2"-O-cinnamoyl-6"-O-galloyl)-glucopyranoside and 4-(4'-hydroxyphenyl)-2-butanone-4'-O-β-D-(2"-O-galloyl-6"-O-p-coumaroyl)-glucopyranoside were isolated from the root and rhizome of Rheum tanguticum for the first time.