CAJ | 학술논문

背景:新型止血材料SURGICELTM在其他科室显微手术中已取得较好的临床效果,而在神经外科中尚无前瞻性随机对照的研究结果报道.目的:比较明胶海绵和新型止血材料SURGICELTM 控制神经外科术中出血及局部渗血的效果.方法:选择苏州市立医院神经外科2008-04/2010-12 进行颅脑手术的患者60例,按随机数字表法分为SURGICELTM止血组30 例和明胶海绵止血组30 例.术中各自使用这两种止血材料进行止血.结果与结论:明胶海绵止血组止血失败率为10%(3/30),显著高于SURGICELTM止血组[3%(1/30)],差异有显著性意义(P<0.05).SURGICELTM 止血组止血时间为(2.43±0.75) min,明胶海绵止血组止血时间为(4.23±0.89) min,两组比较差异有显著性意义(P<0.05),术后均未发生过敏反应和排斥反应.新型止血材料SURGICELTM较传统明胶海绵可以更迅速地控制神经外科手术中的出血及局部渗血,止血成功率明显提高.
배경:신형지혈재료SURGICELTM재기타과실현미수술중이취득교호적림상효과,이재신경외과중상무전첨성수궤대조적연구결과보도.목적:비교명효해면화신형지혈재료SURGICELTM 공제신경외과술중출혈급국부삼혈적효과.방법:선택소주시립의원신경외과2008-04/2010-12 진행로뇌수술적환자60례,안수궤수자표법분위SURGICELTM지혈조30 례화명효해면지혈조30 례.술중각자사용저량충지혈재료진행지혈.결과여결론:명효해면지혈조지혈실패솔위10%(3/30),현저고우SURGICELTM지혈조[3%(1/30)],차이유현저성의의(P<0.05).SURGICELTM 지혈조지혈시간위(2.43±0.75) min,명효해면지혈조지혈시간위(4.23±0.89) min,량조비교차이유현저성의의(P<0.05),술후균미발생과민반응화배척반응.신형지혈재료SURGICELTM교전통명효해면가이경신속지공제신경외과수술중적출혈급국부삼혈,지혈성공솔명현제고.
BACKGROUND: A novel hemostatic material SURGICELTM has achieved good clinical results in the micro -surgery of many sections, and in neurosurgery, there is no prospective randomized controlled study reported.OBJECTIVE: To compare the efficacy of SURGICELTM and gelatin sponge in the management of active and local bleeding in neurosurgery.METHODS: Sixty patients undergoing cranial neurosurgery in the Department of Neurosurgery, Suzhou Municipal Hospital between April 2008 and December 2010 were randomized into the SURGICELTM group (n=30) and gelatin sponge group (n=30)with the use of SURGICELTM and gelatin sponge as hemostatic materials, respectively.RESULTS AND CONCLUSION: One case of hemostasis failed in the SURGICELTM group, whereas 3 cases failed in the gelatinsponge group. The failure rate of the gelatin sponge group was 10%, significantly higher than that of the SURGICELTM group (3%,P<0.05). The mean hemostasis time in the SURGICELTM group and gelatin sponge group was (2.43±0.75) and (4.23±0.89)minutes, respectively, showing a significant difference between the two group (P<0.05). No allergic reaction and rejection occurred postoperatively. SURGICELTM allows faster hemostatic effect and larger hemostatic success rate than gelatin sponge during neurosurgeries.