CAJ | 학술논문

目的探讨主动性心肺复苏对犬心室颤动(室颤)时心功能的影响.方法应用经胸二维超声心动图分别测量犬室颤时主动性心肺复苏组(ACD-CPR组,12只)和标准心肺复苏组(S-CPR组,12只)左心室舒张末期容积、左心室收缩末期容积,计算左心室射血分数(LVEF),比较两组间各项测量结果.结果室颤时,两组左心室舒张末期容积较室颤前均有下降,但差异均无统计学意义(P＞0.05);两组左心室收缩末期容积较室颤前显著增大,差异有统计学意义(P＜0.001).CPR时,ACD-CPR组比S-CPR组左室舒张末期容积增加,但差异无统计学意义(P＞0.05);前者比后者左室收缩末期容积减少,但差异无统计学意义(P＞0.05).CPR时,ACD-CPR组与S-CPR组LVEF较室颤前显著下降,差异有统计学意义(P＜0.001);前者LVEF较后者显著增加,差异有统计学意义(P=0.019).结论主动性心肺复苏较常规心肺复苏有助于改善左心室功能.
목적 탐토주동성심폐복소대견심실전동(실전)시심공능적영향.방법 응용경흉이유초성심동도분별측량견실전시주동성심폐복소조(ACD-CPR조,12지)화표준심폐복소조(S-CPR조,12지)좌심실서장말기용적、좌심실수축말기용적,계산좌심실사혈분수(LVEF),비교량조간각항측량결과.결과 실전시,량조좌심실서장말기용적교실전전균유하강,단차이균무통계학의의(P＞0.05);량조좌심실수축말기용적교실전전현저증대,차이유통계학의의(P＜0.001).CPR시,ACD-CPR조비S-CPR조좌실서장말기용적증가,단차이무통계학의의(P＞0.05);전자비후자좌실수축말기용적감소,단차이무통계학의의(P＞0.05).CPR시,ACD-CPR조여S-CPR조LVEF교실전전현저하강,차이유통계학의의(P＜0.001);전자LVEF교후자현저증가,차이유통계학의의(P=0.019).결론 주동성심폐복소교상규심폐복소유조우개선좌심실공능.
Objective To compare the effect of active compression-decompression cardiopulmonary resuscitation(ACD-CPR) with standard- cardiopulmonary resuscitation(S-CPR) on ventricular function in a canine ventricular fibrillation model. Methods Ventricular fibrillation was induced in anesthetized and instrumented canine. Twenty-four dogs were randomly assigned to either ACD-CPR group or S-CPR group.After 4 minutes of untreated VF,two-dimension echocardiography was used to evaluate the left ventricular end-diastolic volume(LVEDV),left ventricular end-systolic volume(LVESV) and left ventricular ejection fraction (LVEF) of every canine of the two groups when they were undergoing cardiopulmonary resuscitation. Results During ventricular fibrillation, both ACD-CPR group and S-CPR group showed decreased LVEDV compared with pre-ventricular fibrillation, but not statistically significant( P ＞0.05).LVEDV was increased in ACD-CPR group compared with S-CPR group, but not statistically significant (P＞ 0. 05). Both ACD-CPR group and S-CPR group showed significantly increased LVESV compared with pre-ventricular fibrillation,of which the difference was statistically significant ( P ＜0. 001). Both ACD-CPRgroup and S-CPR group showed significantly decreased LVEF compared with pre-ventricular fibrillation,of which the difference was statistically significant (P ＜0. 001). LVEF was increased in ACD-CPR group compared with S-CPR group,of which the difference was statistically significant ( P = 0.019). Conclusions Compared with S-CPR,ACD-CPR resulted in higher LVEF.