CAJ | 학술논문

目的探讨解脲支原体(UU)、沙眼衣原体(CT)感染与自然流产的相关性，为临床决策提供依据。对女性生殖道与宫内胚胎间UU，CT感染的关系进行评价。方法自然流产(研究组)和人工流产(对照组)妇女各30例，留取宫颈管分泌物和绒毛组织，采用聚合酶链反应技术(PCR)进行UU-DNA，CT-DNA检测。随机抽取了其中的8例绒毛标本进行光镜和电镜的组织学检查。结果生殖道UU，CT检出阳性者研究组分别为10.0％，33.3％，对照组分别为20.0％，43.3％，差异无显著性(P>0.05)。绒毛UU，CT检出阳性者研究组分别为16.7％，26.7％，对照组为33.3％，30.0％，差异无显著性(P>0.05)。生殖道UU，CT阳性者37.9％绒毛中检出同种病原体，阴性者中48.4％绒毛UU，CT阳性。两者差异无显著性(P>0.05)。组织学检查未发现UU，CT感染的绒毛标本具特异性改变。结论生殖道及妊娠组织的UU，CT感染并不增加早期妊娠丢失，宫颈管UU，CT的存在不是导致宫内胚胎感染的决定因素。
목적탐토해뇨지원체(UU)、사안의원체(CT)감염여자연유산적상관성，위림상결책제공의거。대녀성생식도여궁내배태간UU，CT감염적관계진행평개。방법자연유산(연구조)화인공유산(대조조)부녀각30례，류취궁경관분비물화융모조직，채용취합매련반응기술(PCR)진행UU-DNA，CT-DNA검측。수궤추취료기중적8례융모표본진행광경화전경적조직학검사。결과생식도UU，CT검출양성자연구조분별위10.0％，33.3％，대조조분별위20.0％，43.3％，차이무현저성(P>0.05)。융모UU，CT검출양성자연구조분별위16.7％，26.7％，대조조위33.3％，30.0％，차이무현저성(P>0.05)。생식도UU，CT양성자37.9％융모중검출동충병원체，음성자중48.4％융모UU，CT양성。량자차이무현저성(P>0.05)。조직학검사미발현UU，CT감염적융모표본구특이성개변。결론생식도급임신조직적UU，CT감염병불증가조기임신주실，궁경관UU，CT적존재불시도치궁내배태감염적결정인소。
Objective To study the relationship UU and CT infection in spontaneous abortion and the relationship between of UU and CT infection in female genital tract and embryos in utero. Methods Sixty early pregnant women were divided into study group (spontaneous abortion n = 30) and control group (induced abortion n=30). Samples were taken from cervical canal and villus tissue. The polymerase chain reation technique was used to detect UU - DNA and CT - DNA.Eight villus specimens were examined under light and electron microscope. Results The positive rate UU and CT infections in genital tract was 10.0% and 33.3% respectively in the study group and was while 20.0% and 43.3% in control group respectively. There were not significant differences between the two groups (P>0.05). The positive rate of villus UU and CT infections was 16.7% and 26.7% in study group and was 33.3% and 30.0% in control group respectively. There were not significant differences. 37.9% of genital tract UU and CT positive women and 48.4% of negative women were detected to have the same pathogen in villus, but there were not significant differences in two groups. Histological examination did not found specific change among the villus specimens infected by UU and CT. Conclusion Female genital tract and pregnant tissue infected by UU and CT dose not increase early pregnant lose. Detection of UU and CT in cervical canal is not the decisive factor causing embryo infection in utero.