CAJ | 학술논문

目的:观察行气活血法对2型糖尿病气滞血瘀证患者血小板活化因子及血浆内皮素、一氧化氮的影响.方法:104例患者,随机分为治疗组53例,对照组51例;治疗组服用加味桃红四物汤,对照组服用桃红四物汤;观察两组临床疗效、血黏度、CD62p、CD63、PAC-1和ET、NO的变化.结果:两组治疗前后组内比较,血黏度、CD62p、CD63、PAC-1和ET、NO的差异,治疗组有非常显著性意义(P＜0.01),对照组有显著性意义(P＜0.05);组间比较,差异有显著性意义(P＜0.05).结论:行气活血法能降低2型糖尿病患者的血黏度,抑制血小板活化,调节内皮素和一氧化氮的分泌失衡,作用较活血化瘀法显著.
목적:관찰행기활혈법대2형당뇨병기체혈어증환자혈소판활화인자급혈장내피소、일양화담적영향.방법:104례환자,수궤분위치료조53례,대조조51례;치료조복용가미도홍사물탕,대조조복용도홍사물탕;관찰량조림상료효、혈점도、CD62p、CD63、PAC-1화ET、NO적변화.결과:량조치료전후조내비교,혈점도、CD62p、CD63、PAC-1화ET、NO적차이,치료조유비상현저성의의(P＜0.01),대조조유현저성의의(P＜0.05);조간비교,차이유현저성의의(P＜0.05).결론:행기활혈법능강저2형당뇨병환자적혈점도,억제혈소판활화,조절내피소화일양화담적분비실형,작용교활혈화어법현저.
To observe the effects of promoting flow of qi and blood circulation method on platelet-activating factor, plasma endothelin and nitric oxide of patients with diabetes type 2 of qi stagnation and blood stasis.Meothods: 104 cases were divided into two groups, 53 cases was treatment group, 51 cases was control. Treatment group was given jiawei taohong siwu decoction, control was given taohong siwu decoction. The changes of clinical symptoms, blood viscosity,CD62p, CD63, PAC-1, ET and NO were observed and recorded.Results: To compare with before treated, the changes of clinical symptoms, blood viscosity,CD62p, CD63, PAC-1, ET and NO were improved after treated with jiawei taohong siwu decoction or taohong siwu decoction, there was obvious difference between treatment and control groups.Conclusion: The effects of promoting flow of qi and blood circulation method on diabetes type 2 of qi stagnation and blood stasis were veritable.