高等学校化学学报
高等學校化學學報
고등학교화학학보
CHEMICAL JOURNAL OF CHINESE UNIVERSITIES
2009年
12期
2415-2418
,共4页
N,N-二[二(3-甲氧基丙基)膦基乙基]-2-乙氧基乙胺盐酸盐%叔膦配合物%2-乙氧基乙胺%3-氯-1-丙醇
N,N-二[二(3-甲氧基丙基)膦基乙基]-2-乙氧基乙胺鹽痠鹽%叔膦配閤物%2-乙氧基乙胺%3-氯-1-丙醇
N,N-이[이(3-갑양기병기)련기을기]-2-을양기을알염산염%숙련배합물%2-을양기을알%3-록-1-병순
Bis ( dimethoxypropylphosphinoethyl)-ethoxyethylamine ( PNP5 ) hydrochloride%Tertiary phos phine complex%2-Ethoxyethylamine%3-Chloro-1-propanol
以2-乙氧基乙胺和3-氯-1-丙醇等为起始原料,经7步反应,制备了N,N-二[二(3-甲氧基丙基)膦基乙基]-2-乙氧基乙胺(PNP5)盐酸盐,其中关键步骤是后两步.PNP5盐酸盐的结构和组成通过IR,~1H NMR,~(13)C NMR,~(31)P NMR,MS和元素分析等方法确认.
以2-乙氧基乙胺和3-氯-1-丙醇等為起始原料,經7步反應,製備瞭N,N-二[二(3-甲氧基丙基)膦基乙基]-2-乙氧基乙胺(PNP5)鹽痠鹽,其中關鍵步驟是後兩步.PNP5鹽痠鹽的結構和組成通過IR,~1H NMR,~(13)C NMR,~(31)P NMR,MS和元素分析等方法確認.
이2-을양기을알화3-록-1-병순등위기시원료,경7보반응,제비료N,N-이[이(3-갑양기병기)련기을기]-2-을양기을알(PNP5)염산염,기중관건보취시후량보.PNP5염산염적결구화조성통과IR,~1H NMR,~(13)C NMR,~(31)P NMR,MS화원소분석등방법학인.
[~(99m)TcN ( PNP5 ) (DTC)] ~+ [PNP5 : bis ( dimethoxypropylphosphinoethyl ) -ethoxyethylamine,DTC: dithiocarbamate] heterocomplexes can be viewed as resulting from the selective coupling of the metal fragment [~(99m)TcN (PNP5)]~(2+) with the bidentate dithiocarbamate π-donor ligand, and these complexes have attractive potential for myocardial perfusion imaging agents. In this article, PNP5 hydrochloride was synthesized from 2-ethoxyethylamine and 3-chloro-1-propanol through seven steps successively, in which the last two steps were the key. The structure of PNP5 hydrochloride was affirmed by IR, ~1H NMR, ~(13)C NMR, ~(31)p NMR,MS and Elemental analysis.
