合成化学
閤成化學
합성화학
CHINESE JOURNAL OF SYNTHETIC CHEMISTRY
2009年
6期
705-707
,共3页
尹彦冰%姜海燕%马洁%杨颖%张宏波%谷振华
尹彥冰%薑海燕%馬潔%楊穎%張宏波%穀振華
윤언빙%강해연%마길%양영%장굉파%곡진화
肉桂酰基烯酮二苄硫缩醛%迈克尔加成反应%四氢咪唑并[1,2-a]吡啶酮%合成
肉桂酰基烯酮二芐硫縮醛%邁剋爾加成反應%四氫咪唑併[1,2-a]吡啶酮%閤成
육계선기희동이변류축철%매극이가성반응%사경미서병[1,2-a]필정동%합성
α-cinnamoyl-dibenzyl-thioacetals%Aza-Michael addition reaction%tetrahydroimidazo[1,2-a]pyridone%synthesis
在三乙胺催化下,α-肉桂酰基烯酮二苄硫缩醛与乙二胺反应形成α-羰基-N,N-缩烯酮类化合物,其进一步发生分子内迈克尔加成反应,以中等产率合成了3个新型的取代四氢咪唑并[1,2-a]吡啶酮类化合物,其结构经1H NMR和IR表征.对反应机理进行了初步探讨.
在三乙胺催化下,α-肉桂酰基烯酮二芐硫縮醛與乙二胺反應形成α-羰基-N,N-縮烯酮類化閤物,其進一步髮生分子內邁剋爾加成反應,以中等產率閤成瞭3箇新型的取代四氫咪唑併[1,2-a]吡啶酮類化閤物,其結構經1H NMR和IR錶徵.對反應機理進行瞭初步探討.
재삼을알최화하,α-육계선기희동이변류축철여을이알반응형성α-탄기-N,N-축희동류화합물,기진일보발생분자내매극이가성반응,이중등산솔합성료3개신형적취대사경미서병[1,2-a]필정동류화합물,기결구경1H NMR화IR표정.대반응궤리진행료초보탐토.
α-Carbonyl-N,N-acetals were prepared via the reaction of α-cinnamoyl-dibenzyl-thioacetals with ethylenediamine using triethylamine as the catalyst, Further, intramolecular Aza-Michael addition reactions occurred, and three new tetrahydroimidazo[1,2-a]pyridone compounds in moderate yields were synthesized. A mechanism for this Aza-Michael addition reaction is proposed preliminarily.
